Comparison of the Effects of Metoprolol and Bisoprolol on Lipid and Glucose Profiles in Cardiovascular Patients.

Curr Drug Saf

Family and Community Medicine Department, Unaizah College of Medicine and Medical Sciences, Qassim University, Qassim, Saudi Arabia.

Published: May 2019

AI Article Synopsis

  • The study aimed to compare the effects of two beta-blockers, metoprolol and bisoprolol, on glucose and lipid profiles in patients with cardiovascular diseases.
  • It was conducted as a retrospective cross-sectional matched study at the Prince Sultan Cardiac Center in 2017, involving adult patients on stable doses of either drug.
  • The final analysis included 204 patients on metoprolol and 200 on bisoprolol, with metabolic parameters compared using the Student's t-test.

Article Abstract

Background: Cardioselective beta-blockers may affect glucose or lipid profiles.

Objective: We sought to compare the effects of two beta-blockers, metoprolol and bisoprolol, as the most commonly used drugs in cardiology, on glucose and lipid profiles in patients with cardiovascular diseases.

Methods: We conducted a retrospective cross-sectional matched study at Prince Sultan Cardiac Center in Burydah in August 2017. Patient records were screened, and adult patients with cardiovascular disorders who were treated with a stable dose of metoprolol or bisoprolol were included. Parameters related to glucose and lipid metabolism were compared using the Student's t-test between the two groups.

Results And Conclusion: The metoprolol and bisoprolol arms included 204 and 200 patients, respectively.

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Source
http://dx.doi.org/10.2174/1574886313666181029101247DOI Listing

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