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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202067PMC
http://dx.doi.org/10.1055/a-0752-9715DOI Listing

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Background: Myofibroblastic sarcoma or myofibrosarcoma is a malignant tumor of myofibroblasts and known to develop rarely in the breast, but its underlying lesion and tumor cell origin have never been reported yet.

Case Presentation: A 61-year-old female presented with a gradually growing breast mass with well-demarcated ovoid nodular shape. The tumor was histologically characterized by fascicular-growing spindle cell proliferation with large areas of hyalinized fibrosis and focally ductal epithelial remnants embedded in myxoid stroma, mimicking a fibroadenomatous lesion.

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Myofibrosarcoma: a clinicopathologic study.

Am J Surg Pathol

February 2001

Department of Pathology, Georgetown University, Washington, DC, USA.

The concept of soft tissue sarcomas composed predominantly of myofibroblasts has been controversial. We examined a series of such lesions of low- and intermediate-grade malignancy to further define their clinical and pathologic features. Histologic appearances of four cases diagnosed as myofibrosarcoma by electron microscopy were reviewed.

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