STEREOSELECTIVE REDUCTION OF α-HYDROXY OXIME ETHERS: A CONVENIENT ROUTE TO CIS-1,2-AMINO ALCOHOLS.

Tetrahedron Lett

Department of Chemistry, Merck Sharp & Dohme Research Laboratories West Point, Pennsylvania 19486.

Published: February 1991

Reduction of cyclic α-hydroxyketoximes with borane provides an excellent, high yielding, regio- and stereoselective route to CIS-1, 2-amlnoalcohols.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200347PMC
http://dx.doi.org/10.1016/S0040-4039(00)74864-7DOI Listing

Publication Analysis

Top Keywords

stereoselective reduction
4
reduction α-hydroxy
4
α-hydroxy oxime
4
oxime ethers
4
ethers convenient
4
convenient route
4
route cis-12-amino
4
cis-12-amino alcohols
4
alcohols reduction
4
reduction cyclic
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!