AI Article Synopsis
- The study analyzed desaturation rates during general anesthesia in pediatric and adult patients, comparing those who were hypoxic (SpO2 < 92%) to nonhypoxic patients.
- Pediatric patients had a desaturation incidence of 11.1%, while adults had only 0.9%, indicating a significantly higher risk in children.
- Hypoxic individuals, both pediatric and adult, faced much greater risks of desaturation; pediatric hypoxic patients had a 2.5 times higher risk, while hypoxic adults were 20.1 times more at risk compared to their nonhypoxic counterparts.
Article Abstract
We investigated the incidence of desaturation during general anesthesia in preoperatively hypoxic (< 92%), and nonhypoxic (≥ 92%) pediatric (n=1,090) and adult (n=5,138) patients. We plotted the patients' SpO2 value time-courses and assessed desaturation in 6,228 patients. The crude overall incidence (95%CI) for desaturation was 11.1% (9.4-13.1) in the pediatric patients and 0.9% (0.6-1.2) in the adults. The crude incidence of desaturation in the hypoxic pediatric patients was 2.5 times the risk in the nonhypoxic patients: risk ratio (RR) 2.5 (1.8-3.5), p<0.001. The risk of desaturation in the hypoxic adult patients was 20.1 times the risk in the nonhypoxic adult patients: RR 20.1 (10.3-39.2), p<0.001. When the patients were separately stratified by American Society of Anesthesiologists Physical Status (ASA-PS) and by age, the directly adjusted risk-ratio (RRS) showed that the hypoxic pediatric patients had 1.8 and 1.6 times the risk in the nonhypoxic pediatric patients: ASA-PS adjusted RRS 1.6 (1.8-2.2), p<0.001; age-adjusted RRS 1.8 (1.3-2.5), p<0.001, and the hypoxic adult patients had 13.8 times the risk in the nonhypoxic adult patients: RRS 13.8 (6.9-27.6), p<0.001. A pulse-oximeter check before the start of general anesthesia could ensure timely preparation to avoid intraoperative desaturation.
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| http://dx.doi.org/10.18926/AMO/56244 | DOI Listing |
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