AI Article Synopsis
- Pigmented villonodular synovitis (PVNS) is a rare, benign but aggressive growth mainly seen in large joints, and less commonly in the spine, where it typically affects the posterior elements.
- PVNS can be mistaken for serious conditions like malignant tumors due to its similar lytic appearance on imaging and fludeoxyglucose uptake.
- A case study of a 49-year-old woman with confirmed PVNS of the cervical spine illustrates the importance of imaging work-up and histopathological analysis in correctly diagnosing this condition.
Article Abstract
Pigmented villonodular synovitis (PVNS) is an uncommon, benign, but locally aggressive lesion characterized most commonly by synovial proliferation of the appendicular large joints, but occasionally involving a bursa or the tendon sheath. PVNS of the spine is rare, typically involving the posterior elements. The lytic radiographic appearance and fludeoxyglucose avidity of PVNS may mimic malignant bone lesions, including metastatic disease or myeloma. On and weighted, and gradient recalled echo MRI sequences, the low signal intensity may mimic giant cell tumour of the bone, gout or synovial amyloid deposits, thus posing a diagnostic dilemma for the imagers and the treating clinicians. We present a pathologically confirmed case of PVNS of the cervical spine in a 49-year-old female, detailing her imaging work-up, describing histopathological correlation and highlighting the lesion location and involvement of the joint space as useful imaging discriminators for diagnosing PVNS of the cervical spine.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195912 | PMC |
| http://dx.doi.org/10.1259/bjrcr.20150264 | DOI Listing |
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