AI Article Synopsis
- Cancer can develop after solid organ transplants, particularly due to viral infections, with HHV-8 causing Kaposi's sarcoma (KS).
- A case is presented of a 15-year-old girl who developed visceral KS rapidly following lung transplantation, with lesions found in multiple organs but not on the skin.
- The report emphasizes the need for increased awareness among pediatric transplant teams about this rare complication, especially since the patient was not tested for HHV-8 before the transplant.
Article Abstract
Cancer is a major adverse outcome of solid organ transplantation, and risks are especially high for malignancies caused by viral infections. HHV-8 is the etiologic agent of Kaposi´s sarcoma (KS). We report a case of visceral KS occurring in a 15-year-old patient after lung transplantation. The evolution was dramatically fast and interestingly, KS lesions were diffusely observed, but not in the skin. The autopsy showed the presence of numerous tumoral lesions in many organs. Microscopically, they all had very similar features, regardless of the organ affected. KS presented without cutaneous involvement. The girl was not tested for HHV-8 prior to transplantation as it was not part of our protocol. The donor was negative. The aim of the report is to alert other teams, especially those working in pediatrics, about this rare but potential complication in the setting of solid organ transplantation.
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| http://dx.doi.org/10.1111/petr.13311 | DOI Listing |
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