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detected in pleural effusion fluid: A case report.
Biomed Rep
February 2025
Department of Laboratory Medicine, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi 046000, P.R. China.
is predominant in dental caries and is commonly observed in patients with oral diseases; however, its presence in patients with pleural effusion remains rare. Pleural effusion can arise from various causes, including malignant tumors, tuberculosis and bacterial infections. Concurrent infections involving bacteria, fungi and are infrequent.
View Article and Find Full Text PDFAnti-Bacterial and Anti-Dermatophytic Activity of Extracellular Secondary Metabolites of Streptomyces glaucescens NTSB-37 Isolated from Lichen Parmotrema perlatum (Huds.) M. Choisy in Kolli Hills, Tamil Nadu, India.
Curr Microbiol
December 2024
B.S.Abdur Rahman Crescent Institute of Science & Technology, Chennai, Tamil Nadu, 600048, India.
Lichen-associated endophytic Actinobacteria, particularly Streptomyces species, are recognized for their production of bioactive secondary metabolites with significant pharmaceutical potential. With the escalating prevalence of diseases, Streptomyces species are being investigated for its natural source of antimicrobial compounds for new antibiotics. This study focuses on the bioactive properties of secondary metabolites from lichen-associated endophytic Actinobacteria, focusing on Streptomyces glaucescens NTSB-37 isolated form lichen, Parmotrema perlatum (Huds.
View Article and Find Full Text PDFIron triggers PI4P5K proteostasis and Arf-mediated cell membrane trafficking to regulate PIP signaling crucial for multiple pathogenic activities of the parasitic protozoan .
mBio
December 2024
Department of Tropical Medicine and Parasitology, College of Medicine, National Taiwan University, Taipei, Taiwan.
is the etiologic agent of trichomoniasis, one of the most common non-viral sexually transmitted infections globally. Our previous work reported the role of phosphatidylinositol 4,5-bisphosphates (PIP) signaling in the actin-dependent pathogenicity of . This study further demonstrated that iron transiently regulated phosphatidylinositol-4-phosphate 5-kinase (PI4P5K) proteostasis and its complex formation with an active ADP ribosylation factor Arf220, facilitating co-trafficking to the plasma membrane, crucial for PIP production.
View Article and Find Full Text PDFRole of histone modification in chromatin-mediated transcriptional repression in protozoan parasite Trichomonas vaginalis.
BMB Rep
December 2024
Department of Tropical Medicine, Institute of Tropical Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea.
Trichomonas vaginalis is an extracellular flagellated protozoan responsible for trichomoniasis, one of the most prevalent nonviral sexually transmitted infections. To persist in its host, T. vaginalis employs sophisticated gene regulation mechanisms to adapt to hostile environmental conditions.
View Article and Find Full Text PDFTranscriptome and Evolutionary Analysis of Pseudotrichomonas keilini, a Free-Living Anaerobic Eukaryote.
Genome Biol Evol
December 2024
School of Biological Sciences, University of Bristol, Bristol BS8 1TH, UK.
The early evolution of eukaryotes and their adaptations to low-oxygen environments are fascinating open questions in biology. Genome-scale data from novel eukaryotes, and particularly from free-living lineages, are the key to answering these questions. The Parabasalia are a major group of anaerobic eukaryotes that form the most speciose lineage of Metamonada.
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