Objective:: The objective of this work is to characterise out- of- field leakage radiation emanating from clinical applicators of the WOmed T-200 kilovoltage therapy machine.
Methods:: To identify points of leakage, radiosensitive film was affixed to the walls and base plate of each applicator. Quantitative assessment of leakage radiation was conducted with a 0.23 cm ionisation chamber following the International Electrotechnical Commission standard. Film was also used to illustrate leakage distribution in the patient plane. Angular and energy dependences of the leakage radiation were quantified as well as a two-dimensional leakage profile in the plane parallel to one applicator.
Results:: Leakage was found when the diameter of primary collimator of the kV tube exceeded the external dimension of the applicator wall. In the patient plane all applicators showed similar leakage rates with the leakage distribution dependent upon applicator design. Mean patient plane leakage was 1.37% of central axis air kerma rate, exceeding the 0.5% limit specified in the standard. Leakage was shown to be profoundly energy dependent with maximum leakage of 11.8% for the 200 kV beam, 1.3% for 150 kV and 0.2% for 100 kV. Angular dependence measurements showed a 10.3% change in leakage between the minimum and maximum positions.
Conclusion: The combination of shielding thickness, primary collimator design and applicator dimensions permits unwanted radiation to contribute dose outside the treatment field when energies ≥150 kV are used.
Advances In Knowledge:: Even carefully designed modern kv therapy systems can exhibit leakage in some areas. Thorough assessment of leakage is needed prior to release for clinical use.
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http://dx.doi.org/10.1259/bjr.20180743 | DOI Listing |
BMC Surg
January 2025
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital & Institute, Beijing, 100142, China.
Background: Globally, totally laparoscopic total gastrectomy is increasingly being accepted by surgeons for the treatment of gastric cancer. Overlap anastomosis and π-shaped anastomosis are the two most commonly used anastomosis methods in total laparoscopic surgery; however, their safety and suitability for the population are still unclear.
Methods: A total of 162 consecutive patients with gastric cancer who underwent total laparoscopic total gastrectomy with overlap or π-shaped anastomosis were retrospectively analyzed.
Environ Sci Pollut Res Int
January 2025
Slovak Hydrometeorological Institute, Jeséniova 17, Bratislava, 833 15, Slovakia.
This study focused on testing the response of the assimilation apparatus of evergreen Pinaceae species to increasing levels of oxidative stress simulated in manipulative experiments. Needles were collected from mature individuals of Pinus mugo, Pinus cembra, Pinus sylvestris, Abies alba, and Picea abies at the foothill (FH) and alpine treeline ecotone (ATE) in the High Tatras (Western Carpathians). The injury index (INX), quantified by the modified electrolyte leakage (EL) method, indicated severe needle damage due to exposure to extremely high levels of O.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Agronomy, Faculty of Agriculture and Environment, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Potato is cultivated all the year round in Pakistan. However, the major crop is the autumn crop which is planted in mid-October and contributes 80-85% of the total production. The abrupt climate change has affected the weather patterns all over the world, resulting in the reduction of the mean air temperature in autumn by almost 1.
View Article and Find Full Text PDFTransl Psychiatry
January 2025
Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Anxiety disorder, a prevalent mental health issue, is one of the leading causes of disability worldwide. Damage to the blood-brain barrier (BBB) is implicated in anxiety, but its regulatory mechanisms remain unclear. Herein, we show that adrenomedullin 2 (ADM2), a novel angiogenic growth factor, alleviates autistic and anxiety-like behaviors in mice.
View Article and Find Full Text PDFMedicine (Baltimore)
November 2024
Department of Cardiovascular Surgery, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi Province, China.
Background: Transcatheter closure of percutaneous paravalvular leak (PVL) is a technically challenging procedure, especially after surgical mechanical valve replacements (SMVR), as the risk of interference with the prosthetic valve discs and the complex interventional techniques required for mitral PVL closure. Our study was designed to review the results with transcatheter closure of PVL after SMVR.
Methods: From January 2018 through December 2023, a total of 64 patients with PVL after SMVR underwent transcatheter closure with the help of preoperative 3-dimensional printing model and simulator for image evaluation.
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