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Four-Component Domino Synthesis of Pyrazolo[3,4- h]quinoline-3-carbonitriles: "Turn-Off" Fluorescent Chemosensor for Fe Ions. | LitMetric

AI Article Synopsis

  • A new method was developed to create pyrazolo[3,4-h]quinoline-3-carbonitriles through a one-pot, four-component reaction using microwave technology without solvents.
  • One of the synthesized compounds displayed fluorescence when exposed to UV light.
  • This compound also showed a strong sensitivity to iron ions in DMSO, with a detection limit of 8.6 × 10 M compared to other metal ions.

Article Abstract

The synthesis of novel pyrazolo[3,4- h]quinoline-3-carbonitriles has been achieved through a one-pot, four-component domino strategy under solvent-free microwave conditions. One of these compounds exhibited fluorescence under UV lamp and was found to be highly sensitive toward Fe ions in DMSO against various metal ions with a detection limit of 8.6 × 10 M.

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Source
http://dx.doi.org/10.1021/acs.joc.8b01991DOI Listing

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