A 75-year-old man was referred to our department because of discolouration of his tongue and an elevated CRP. Clinical examination did not reveal any other abnormalities. Blood examination showed an excessive amount of leukocytes with low platelet and erythrocyte counts. These findings indicated an atypical presentation of acute myeloid leukaemia.
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[Alkaptonuria: evolution and course of the disease towards ochronotic arthropathy. Series of cases managed with joint replacement].
Acta Ortop Mex
November 2023
Universidad Pontificia Bolivariana. Medellín, Colombia.
Introduction: alkaptonuria is a very rare metabolic disease with autosomal recessive inheritance due to HGA oxidase deficiency. Classically described and diagnosed in the third to fourth decade of life, affecting both men and women; Its diagnostic impression is clinical based on the blue/black coloration of the conjunctivae, however it is confirmed by the specific analysis of the enzyme in the urine, to date there is no cure and its treatment is palliative and symptomatic.
Material And Methods: descriptive, observational, case series study, the primary objective of which is to describe the progression of the disease and its involvement in the musculoskeletal system.
[A man with a blue-black discolouration of the tongue].
Ned Tijdschr Geneeskd
September 2018
ETZ Elisabeth, afd. Mond-, Kaak- en Aangezichtschirurgie, Tilburg.
A 75-year-old man was referred to our department because of discolouration of his tongue and an elevated CRP. Clinical examination did not reveal any other abnormalities. Blood examination showed an excessive amount of leukocytes with low platelet and erythrocyte counts.
View Article and Find Full Text PDFGenital angiokeratomas of Fordyce 595-nm variable-pulse pulsed dye laser treatment.
J Cosmet Laser Ther
December 2017
b Department of Dermatology and Venereology , Comenius University, Bratislava , Slovak Republic.
Article Synopsis
- Angiokeratoma of Fordyce (AF) is a benign skin condition characterized by dark papules on the genital area, which can sometimes bleed, creating a need for differentiation from serious conditions like melanoma. !* -
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Introduction: While epidermal growth factor receptor (EGFR) inhibitors have improved progression-free survival in patients with non-small cell lung cancer (NSCLC), one of the most common adverse effects is papulopustular skin eruption, which is frequently severe enough to be treated with oral minocycline or doxycycline.
Case: We present a case of an 87-year-old man who developed a severe papulopustular skin eruption secondary to erlotinib therapy for NSCLC. Control of the eruption with 100 mg of minocycline twice daily for 8 months eventually led to blue-gray skin hyperpigmentation.
Dermoscopic Clues for Diagnosing Melanomas That Resemble Seborrheic Keratosis.
JAMA Dermatol
June 2017
Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria.
Importance: Melanomas that clinically mimic seborrheic keratosis (SK) can delay diagnosis and adequate treatment. However, little is known about the value of dermoscopy in recognizing these difficult-to-diagnose melanomas.
Objective: To describe the dermoscopic features of SK-like melanomas to understand their clinical morphology.
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