A recent prospective epidemiological study suggested that an increase in the nutritional uptake of the natural polyamine spermidine is associated with reduced overall and cancer-specific mortality. Here, we speculate through which mechanisms spermidine might exert such oncopreventive effects. ACLY, ATP citrate lyase; ATG, autophagy-related gene; CoA, coenzyme A; NSCLC, non-small cell lung cancer.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333461 | PMC |
| http://dx.doi.org/10.1080/15548627.2018.1539592 | DOI Listing |
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