A laser-induced rf plasma (LIRFP) ion source was developed to ionize submicrometer-sized particles for the first time. The LIRFP ion source can increase the charge of those particles to several thousand charges via charge exchange reactions so that those particles can be trapped and analyzed with a charge detection quadrupole ion trap-mass spectrometer (CD QIT-MS). Different reagent gases for charge exchange reaction were investigated, viz. argon, nitrogen, oxygen, methane, helium, krypton, xenon, argon/methane (with ratios of 10:1 and 2:1), argon/nitrogen (with a ratio of 1:1), nitrogen/oxygen (10:1), krypton/methane (10:1), and air. The average charge of 0.75 μm polystyrene particles could reach 1631 using an argon/methane mixture with a ratio of ∼10:1. The average charges for freeze-dried Escherichia coli EC11303, Escherichia coli strain W, and Staphylococcus aureus were 842, 1112, and 971, respectively, with a mass-to-charge ratio ( m/ z) range from 10 to 10; and the average masses were 3.5 × 10 Da, 6.0 × 10 Da, and 5.6 × 10 Da, respectively. The average mass and charge of the vaccinia virus were ∼9.1 × 10 Da and ∼708 with a m/ z of ∼10. This LIRFP CD QIT-MS method was rapid with only 20 min for each sample measurement.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.analchem.8b03983 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Restructuring Biologically Assembled Binding Protein-Biopolymer Conjugates toward Advanced Materials.
ACS Appl Mater Interfaces
December 2024
Centre for Cell Factories and Biopolymers, Griffith Institute for Biomedicine and Glycomics, Griffith University, Nathan, QLD 4111, Australia.
Bacterial cell factories have been successfully engineered to efficiently assemble spherical polyhydroxybutyrate inclusions coated with functional proteins of interest. In these submicrometer-sized core-shell assemblies, proteins are bioconjugated to the polymer core, enabling bioengineering for uses as bioseparation resins, enzyme carriers, diagnostic reagents, and particulate vaccines. Here, we explore whether these functional protein-polymer assemblies could be restructured via dissolution and subsequent precipitation while retaining the functionality of the conjugated protein.
View Article and Find Full Text PDFPreparation and Performance Investigation of Carbon-Coated LiMnTiO/C Cathode Materials.
ACS Appl Mater Interfaces
October 2024
State Key Laboratory of Mesoscience and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Mn-based cation disordered rock-salt (DRX) cathode materials exhibit promising application prospects due to their cost-effectiveness and high specific capacity. However, the synthesis methods commonly employed for these materials rely on the solid-state reaction method and mechanochemistry method, primarily attributed to the influence of low-valence states of Mn. Currently, sol-gel approaches for preparing Mn-based DRX cathode materials are limited to systems involving Mn.
View Article and Find Full Text PDFInfluence of Sodium Ions and Carbon Black on the Formation and Structural Color of Photonic Balls by Silica Particles.
Langmuir
September 2024
Department of Molecular & Macromolecular Chemistry, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.
In this study, photonic balls─spherical aggregates of submicrometer-sized silica particles with uniform particle size─were investigated as structural colored materials. The structural color of these photonic balls is influenced by the ordered arrangement of the silica particles. The research focused on how the addition of electrolytes, specifically NaCl, affects the formation of photonic balls to achieve the desired structural color.
View Article and Find Full Text PDFDepletion Flocculation of High Internal Phase Pickering Emulsion Inks: A Colloidal Engineering Approach to Develop 3D Printed Porous Scaffolds with Tunable Bioactive Delivery.
ACS Appl Mater Interfaces
August 2024
Food Oral Processing Laboratory, School of Food Science & Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.
Flocculation is a type of aggregation where the surfaces of approaching droplets are still at distances no closer than a few nanometers while still remaining in close proximity. In a high internal-phase oil-in-water (O/W) emulsion, the state of flocculation affects the bulk flow behavior and viscoelasticity, which can consequently control the three-dimensional (3D)-printing process and printing performance. Herein, we present the assembly of O/W Pickering high-internal-phase emulsions (Pickering-HIPEs) as printing inks and demonstrate how depletion flocculation in such Pickering-HIPE inks can be used as a facile colloidal engineering approach to tailor a porous 3D structure suitable for drug delivery.
View Article and Find Full Text PDFPreparation of Surface-Wrinkled Silica-Polystyrene Colloidal Composite Particles.
Langmuir
June 2024
School of Materials and Chemistry, University of Shanghai for Science and Technology, 516 Jungong Road, Shanghai 200093, China.
In this work, we report a facile emulsion swelling route to prepare surface-wrinkled silica-polystyrene (SiO-PS) composite particles. Submicrometer-sized, near-spherical SiO-PS composite particles were first synthesized by dispersion polymerization of styrene in an ethanol/water mixture, and then, surface-wrinkled SiO-PS particles were obtained by swelling the SiO-PS particles with a toluene/water emulsion and subsequent drying. It is emphasized that no surface pretreatment on the SiO-PS composite particles is required for the formation of the wrinkled surface, and the most striking feature is that the surface-wrinkled particle was not deformed from a single near-spherical SiO-PS composite particle but from many ones.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!