The use of intralipid emulsion therapy to treat severe cardiotoxicity secondary to lamotrigine ingestion in a dog.

Clin Case Rep

Emergency and Critical Care Department BluePearl Veterinary Partners New York New York.

Published: October 2018

Lamotrigine is a sodium and calcium channel blocker, used to treat seizures in people. Dogs metabolize Lamotrigine to a cardiotoxic metabolite that causes severe, often fatal ventricular arrhythmias. This report documents the successful treatment of refractory Lamotrigine cardiotoxicity in a dog, using intralipid emulsion therapy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186877PMC
http://dx.doi.org/10.1002/ccr3.1733DOI Listing

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