Purpose: To evaluate the bleaching efficacy and time required for color stability immediately after dental office bleaching.
Methods: 40 subjects were randomly divided into two groups, according to the bleaching agent used:GHP - 35% hydrogen peroxide gel and GCP - 37% carbamide peroxide gel. The color was measured with a spectrophotometer before and immediately, 24 hours, 72 hours, 7 days and 15 days after the bleaching procedure. The color parameters were evaluated and the ΔE*, ΔL*, Δa* and Δb* values were calculated for each evaluation period. The data was statistically analyzed with Student's T-test, one-way ANOVA and Tukey's post hoc test (P ≤ 0.05).
Results: Regarding the ΔE* values, in the assessed periods there were no significant differences between groups (P≥ 0.05). However, the luminosity (ΔL*) decreased considerably in both groups in the first 72 hours (P≤ 0.05), followed by an increase at 15 days (P≤ 0.05) in the hydrogen peroxide group. Regarding the Δb* values, the GHP showed higher negative alterations in the b* axis in the first 24 hours. The 37% carbamide peroxide gel and the 35% hydrogen peroxide gel were effective and there was no reversal of tooth color within 15 days; however a more accentuated bleaching effect was observed immediately after bleaching.
Clinical Significance: Rapid bleaching was observed immediately after the in-office bleaching treatment.
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Background: Acne treatment can take weeks to deliver noticeable improvements, which may diminish patients' perception of treatment effectiveness and undermine treatment adherence. Combination topical treatments that target multiple acne pathophysiological pathways are more efficacious than topical monotherapies, and simplifying combination treatment by delivering multiple active ingredients as fixed combinations may improve adherence.
Methods: This review provides an overview of efficacy with 4 weeks of treatment in pivotal trials of fixed-combination topical treatments for acne.
J Esthet Restor Dent
January 2025
Department of Physiology and Pathology, School of Dentistry, São Paulo State University (UNESP), Araraquara, Brazil.
Objectives: To evaluate the color change and trans-amelodentinal cytotoxicity of a 22% carbamide peroxide (CP) bleaching gel containing different concentration of manganese oxide (MnO).
Material And Methods: Enamel/dentin discs adapted to artificial pulp chambers were distributed according to treatments: CN-No treatment; CP22%-22%CP; CP22 + 2MnO-22%CP + 2 mg/mLMnO; CP22% + 6MnO-22%CP + 6 mg/mLMnO; CP22% + 10MnO-22%CP + 10 mg/mLMnO applied for 2 h for 15 days. Color change-CC (ΔE and ΔWI) (n = 8) was determined at 5, 10, and 15-day periods (ANOVA/Sidak).
ACS Omega
December 2024
Bioproducts Discovery and Development Centre, Department of Plant Agriculture, Crop Science Building, University of Guelph, 50 Stone Road East, Guelph N1G 2W1, Ontario, Canada.
Recently, there has been immense interest in using biodegradable polymers to replace petro-derived polymers. Poly(3-hydroxybutyrate--3-hydroxyvalerate) (PHBV), which is gaining popularity due to its biodegradability, is used in developing blends and composites for a variety of applications. To enhance the miscibility between different components of a material with PHBV, functionalization of the PHBV chain can be done.
View Article and Find Full Text PDFCureus
November 2024
Conservative Dentistry, Universiti Sains Malaysia, Kota Bharu, MYS.
Dental fluorosis (DF) is a condition affecting tooth enamel that occurs during the development of permanent teeth, resulting from excessive fluoride consumption. Based on the severity, the tooth surface exhibits discoloration or structural anomalies. The range of colors varies from mild discoloration to severe dark brown lesions.
View Article and Find Full Text PDFSci Rep
December 2024
Laboratory of Biochemistry and Vascular Biology, Center for Biologic Evaluation and Research, Food and Drug Administration, Bethesda, 20993, MD, USA.
Blood storage lesion induces cytosolic and membrane changes driven in part by hemoglobin (Hb) oxidation reactions within red blood cells (RBCs). A novel gel formulation containing the antioxidant curcuminoids in a biocompatible solvent system was used to deliver curcumin into RBCs. Incubation of peroxide treated RBCs stored in PBS with curcumin gel led to a reduction in prooxidant ferrylHb and recovery in ATP.
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