Objective: This study investigated the latent dimensional and categorical structure of ICD-11 complex posttraumatic stress disorder (CPTSD) within a refugee sample.
Method: A subsample that identified as refugee (n = 308) was selected from the National Epidemiological Survey on Alcohol and Related Conditions. Factor mixture modeling (FMM) was employed to establish the dimensional structure of CPTSD symptomology and the categorical distribution of these dimensions. It was then evaluated whether trauma history could differentiate between the distribution of trauma response profiles.
Results: A correlated 6-factor model with 5 latent classes was the best fitting model. Two classes were characterized by symptom profiles that were consistent with ICD-11 CPTSD and PTSD formulations. The remaining classes were characterized by nonspecific variation across dimensions. CPTSD class membership was predicted by traumas that were predominantly interpersonal in nature (serious neglect, physical assault, and sexual assault), whereas PTSD class membership was predicted by situational traumatic experiences (unarmed civilian in a conflict environment and a serious accident). A distinct dose-response effect was evident between cumulative traumatic exposure and CPTSD class membership.
Conclusion: FMM class profiles distinguished between PTSD and CPTSD symptom formulations. Moreover, class membership was determined by specific trauma-exposure histories. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
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http://dx.doi.org/10.1037/tra0000408 | DOI Listing |
Ther Adv Hematol
December 2024
Division of Hematology and Oncology, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9255, USA.
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disorder which is caused by mutations in phosphatidylinositol glycan class A leading to hemolysis of red blood cells via complement inhibition. The first treatment for PNH, eculizumab, was FDA approved in 2007. Since then, many new treatment options for PNH have arisen.
View Article and Find Full Text PDFAm J Prev Med
December 2024
Departments of Epidemiology and Health Systems and Population Health, University of Washington, Seattle, WA; Department of Social and Behavioral Sciences, Yale University, New Haven, CT.
Introduction: Healthcare avoidance and delay (HAD) is prevalent among transgender (trans) populations. This study sought to identify patterns of HAD and examine associations between HAD and 5 behavioral health outcomes among trans adults: depression, anxiety, tobacco and alcohol use, and intimate partner violence (IPV).
Methods: This study used survey data collected in 2023 from 789 trans adults in Washington state.
SSM Popul Health
March 2025
Department of Human Development and Family Studies, Purdue University, USA.
Objectives: Using a national sample of Americans, this study estimated and compared patterns of depressive symptom trajectories stratified by military service. This study then examined associations between sociodemographic factors theorized to shape entry into military service and trajectory patterns.
Method: Data came from the National Longitudinal Study of Adolescent to Adult Health, a nationally representative study that followed participants from adolescence (1994-1995) through midlife (2016-2018).
Eur J Neurol
January 2025
Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Background: Upper limb dysfunction is a common debilitating feature of relapsing-remitting multiple sclerosis (RRMS). We aimed to examine the longitudinal trajectory of the iPad®-based Manual Dexterity Test (MDT) and predictors of change over time.
Methods: We prospectively enrolled RRMS patients (limited to Expanded Disability Status Scale (EDSS) < 4).
J Clin Anesth
December 2024
Geisel School of Medicine at Dartmouth, Hanover, NH, United States of America; Department of Anesthesiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States of America. Electronic address:
Background: Frailty, a syndrome of decreased resilience to physiologic stress, has been associated with increased postoperative length of stay (LOS) for specific procedures. Yet, the literature lacks large-scale analyses examining the relationship between frailty and LOS across surgical procedure.
Study Design: We conducted a retrospective cohort study of patients aged 65+ undergoing inpatient surgery including emergency procedures between 2015 and 2019 using American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP®) data.
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