Background: Gastroparesis is a syndrome characterized by delayed gastric emptying in the absence of any mechanical cause. While often associated with diabetes mellitus, most cases of gastroparesis are idiopathic. The purpose of the present paper is to review the co-morbid conditions that most likely associate with non-diabetic gastroparesis.
Methods: The Healthcare Cost and Utilization Project: Nationwide Inpatient Sample (HCUP-NIS) data were used from the year 2013 - 2014 and the Apriori algorithm was run on this subset of patients to identify what co-morbid conditions are most likely associated with gastroparesis.
Results: Notable conditions that were found to be most closely linked with gastroparesis were: chronic pancreatitis, end stage renal disease, irritable bowel syndrome, systemic lupus erythematosus, fibromyalgia, and venous thromboembolism. Some of the implications of these findings are briefly discussed.
Conclusions: Gastroparesis is strongly associated with multiple medical conditions which may be potential targets for treatment.
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http://dx.doi.org/10.14740/gr1060w | DOI Listing |
Diabetes Metab Syndr
November 2024
National Diabetes Obesity and Cholesterol Foundation (N-DOC), New Delhi, India; Diabetes Foundation India, New Delhi, India.
Aim: The prevailing guidelines for obesity in Asian Indians, published in 2009, relied solely on body mass index (BMI) criteria. Recognizing the limitations of BMI in accurately diagnosing obesity and the emergence of new research revealing the association between generalized and abdominal adiposity in Asian Indians and early-onset co-morbid diseases, a comprehensive redefinition was needed.
Method: In a Delphi process focused on obesity in India, experts were invited via email to participate in five rounds.
J Gen Intern Med
January 2025
Center for Chronic Disease Research and Policy, University of Chicago Medicine, Chicago, IL, USA.
Background: Little is known about the population of Medicare beneficiaries with both chronic kidney disease (CKD) and Alzheimer's disease and related dementias (ADRD).
Methods: Using data from Medicare fee-for-service (FFS) beneficiaries aged 65 and over identified through 2011-2019 Master Beneficiary Summary File (MBSF), we estimated the size, growth, and racial-ethnic characteristics of the ADRD and CKD populations. Individuals were classified as having ADRD and CKD based on CMS Chronic Conditions Data Warehouse (CCW) indicators in the MBSF Chronic Conditions file.
Clin Endocrinol (Oxf)
January 2025
Department of Paediatric Endocrinology, Alder Hey Children's Hospital, Liverpool, UK.
Background: Klinefelter syndrome (KS) is an uncommonly recognised condition typified by gynaecomastia, small testes and aspermatogenesis. It is caused by a supernumerary X chromosome, resulting in a 47 XXY karyotype. Since its first description, the phenotype of KS has evolved and there is a much greater appreciation of the subtle features of the condition.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
School of Information Science and Technology, Institute of Computational Biology, Northeast Normal University, Changchun 130117, China.
The aging process will lead to a gradual functional decline in the human body, and even accelerate a significantly increased risk of degenerative diseases. DNA methylation patterns change markedly with one's age, serving as a biomarker of biological age and closely linked to the occurrence and progression of age-related diseases. Currently, diagnostic methods for individual degenerative diseases are relatively mature.
View Article and Find Full Text PDFMymensingh Med J
January 2025
Professor Dr Muhammad Saiful Hasan, Professor and Head, Department of Microbiology and Principal, Netrokona Medical College, Netrokona, Bangladesh; E-mail:
Coronavirus disease-2019 (Covid-19) caused by the virus SARS-CoV 2 is a major health problem across the globe currently. Bangladesh is also defying this highly infectious disease with an exponentially rising number of cases across the country. This study was designed to observe the socio-demographic characteristics, clinical presentation and treatment outcome of Covid-19 cases in Bangladesh.
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