Chronic granulomatous disease (CGD) is associated with multiple and recurrent infections. In patients with CGD, invasive pulmonary infection with aspergillus species remains the greatest cause of mortality. Acute fulminant presentations of fungal pneumonia are catastrophic. It is a medical emergency, and currently the treatment is based on association of corticosteroids and antifungal therapy. We describe the case of an 11-year-old boy, with late initial presentation of CGD, which was revealed by fulminant aspergillus pneumonia. He was successfully treated with an association of high doses of steroids and voriconazole.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.arcped.2018.09.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Chronic granulomatous disease presenting at age 52 with fulminant mulch pneumonitis.
J Allergy Clin Immunol Glob
November 2022
Department of Medicine, Université de Montreal, Montreal, Québec, Canada.
Chronic granulomatous disease should be considered in adults of any age in the presence of refractory and/or atypical or fulminant pulmonary infections. This case of new large deletions in was presented with mulch pneumonitis without a significant history of infections.
View Article and Find Full Text PDFFulminant mulch pneumonitis in a previously healthy child.
Arch Pediatr
November 2018
Department of pediatrics, Sfax Medical School, Hedi Chaker Hospital, Sfax, Tunisia.
Chronic granulomatous disease (CGD) is associated with multiple and recurrent infections. In patients with CGD, invasive pulmonary infection with aspergillus species remains the greatest cause of mortality. Acute fulminant presentations of fungal pneumonia are catastrophic.
View Article and Find Full Text PDFFulminant mulch pneumonitis in undiagnosed chronic granulomatous disease: a medical emergency.
Clin Pediatr (Phila)
December 2010
Auckland Hospital, Auckland, New Zealand.
Fulminant mulch pneumonitis: an emergency presentation of chronic granulomatous disease.
Clin Infect Dis
September 2007
Laboratory of Immune Regulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Background: Chronic granulomatous disease (CGD) is associated with multiple and recurrent infections. In patients with CGD, invasive pulmonary infection with Aspergillus species remains the greatest cause of mortality and is typically insidious in onset. Acute fulminant presentations of fungal pneumonia are catastrophic.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!