This article reflects on an internal evaluation undertaken to estimate the potentials of a community-university pilot project to be developed into a bonafide innovation that can be applied at scale. The focus of the community-university partnership has been to reduce the unintended consequences of medical pluralism on the HIV and AIDS epidemic in Waterberg district, Limpopo Province, South Africa. Despite promising outputs from the partnership - including an increase in adherence to antiretroviral therapy and a reduction in stigma among traditionalists living with HIV - the partnership wished to establish whether further funding should be applied for to take the pilot from its current prototype status to a more established innovation. In order to evaluate the innovative potentials of the pilot, the opportunity vacuum model of innovation was adapted and applied. The findings indicate that (1) the application of the opportunity vacuum model of innovation to evaluate the potentials of the pilot to be developed into a bonafide innovation was fit for purpose and (2) the pilot contains the key ingredients that are associated with innovations in the making. The discussion reflects on the social potentials of the pilot to contribute to 90-90-90 from a global, national and local perspective. The reflection concludes by suggesting that the opportunity vacuum model of innovation is a versatile heuristic that could be applied in other contexts and the community-university pilot represents a nascent innovation which has sufficient potential to justify further development.
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http://dx.doi.org/10.1080/17290376.2018.1536560 | DOI Listing |
BMC Genomics
January 2025
Department of Virology, Norwegian Institute of Public Health, Oslo, 0456, Norway.
The COVID-19 pandemic has underscored the importance of virus surveillance in public health and wastewater-based epidemiology (WBE) has emerged as a non-invasive, cost-effective method for monitoring SARS-CoV-2 and its variants at the community level. Unfortunately, current variant surveillance methods depend heavily on updated genomic databases with data derived from clinical samples, which can become less sensitive and representative as clinical testing and sequencing efforts decline.In this paper, we introduce HERCULES (High-throughput Epidemiological Reconstruction and Clustering for Uncovering Lineages from Environmental SARS-CoV-2), an unsupervised method that uses long-read sequencing of a single 1 Kb fragment of the Spike gene.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Information Technology, Faculty of Computers and Information, Assiut University, Assiut, Assiut, 71515, Egypt.
Fifth-generation (5G) communication technologies, such as millimeter wave communication, massive multiple-input-multiple-output and non-orthogonal-multiple-access (NOMA) are playing a pivotal role in promoting the modern applications of the Internet-of-Things. Using non-orthogonal resource allocation, NOMA can increase spectrum efficiency and achieve wide connectivity with low transmission delay and signaling cost. Despite the high potential of NOMA in 5G communications, NOMA is susceptible to a pilot contamination attack (PCA), in which an attacker resents the same pilot signals as authorized users.
View Article and Find Full Text PDFSci Rep
January 2025
School of Architecture and Urban Planning, Beijing University of Civil Engineering and Architecture, Beijing, 100055, China.
Air pollution is a critical global environmental issue, further exacerbated by rapid industrialization and urbanization. Accurate prediction of air pollutant concentrations is essential for effective pollution prevention and control measures. The complex nature of pollutant data is influenced by fluctuating meteorological conditions, diverse pollution sources, and propagation processes, underscores the crucial importance of the spatial and temporal feature extraction for accurately predicting air pollutant concentrations.
View Article and Find Full Text PDFInt J Psychophysiol
January 2025
Center for Cognitive & Brain Health, Northeastern University, Boston, MA, USA; Department of Physical Therapy, Movement, & Rehabilitation Sciences, Northeastern University, Boston, MA, USA. Electronic address:
Introduction: Prolonged sitting can acutely reduce working memory (WM) in individuals with overweight and obesity (OW/OB) who show executive function deficits. Interrupting prolonged sitting with brief PA bouts may counter these effects. However, the benefits of such interventions on behavioral and neuroelectric indices of WM and whether neurocognitive responses are associated with postprandial glycemic responses in young and middle-aged adults with OW/OB remain unknown.
View Article and Find Full Text PDFJ Contin Educ Nurs
February 2025
Background: New graduate nurses (NGNs) often face challenges during conflicts with health care providers, fellow nurses, and patients.
Method: A pilot educational session was created to address conflict challenges in communication. The session discussed assertive communication, communication tools to be used in practice, and video simulations with standardized clients.
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