Institute of Plant Protection, Chinese Academy of Agricultural Sciences , Beijing 100193 , People's Republic of China.
Published: November 2018
AI Article Synopsis
Article Abstract
The mechanism of NO production following chloropicrin (CP) fumigation was investigated in this study. Our results showed that CP fumigation increased NO production from 23 to 25 times in comparison with the control and significantly decreased the abundance of 16S rRNA and N-cycling functional genes. CP also decreased the soil bacterial diversity and caused a shift in the community composition. The NO emissions in fumigated soil were significantly correlated with soil environmental factors (NH, dissolved amino acid, microbial biomass nitrogen, and NO) but were not correlated with the abundance of functional genes. Metatranscriptomes and dual-label N-O isotope analysis revealed that CP fumigation inhibited the expression of gene families involved in NO production and sink processes and shifted the main pathway of NO production from nitrification to denitrification. These results provided useful information for environmental safety assessments of CP in China, to improve our understanding of the N-cycling pathways in fumigated soils.
NAC [NO APICAL MERISTEM (NAM), ARABIDOPSIS TRANSCRIPTION ACTIVATOR FACTOR 1/2 (ATAF1/2), and CUP-SHAPED COTYLEDON (CUC2)] transcription factors are key regulators of plant growth, development, and stress responses but were also crucial players during land plant adaptation and crop domestication. Using representative members of green algae, bryophytes, lycophytes, gymnosperms, and angiosperms, we expanded the evolutionary history of NAC transcription factors to unveil the relationships among members of this gene family. We found a massive increase in the number of NAC transcription factors from green algae to lycophytes and an even larger increase in flowering plants.
Dioscorea alata, a key tuber crop for global food security, is threatened by anthracnose disease caused by Colletotrichum gloeosporioides. However, identification of functional resistance genes against C. gloeosporioides in D.
Low-frequency non-syndromic hearing loss (LFNSHL) is a rare auditory disorder affecting frequencies ≤ 2000 Hz. To elucidate its genetic basis, we conducted whole-exome sequencing on nine Chinese families (31 affected individuals) with LFNSHL. Four heterozygous pathogenic variants, including two novel variants, were identified in common LFNSHL-related genes (WFS1, DIAPH1) and less common genes (TNC, EYA4), achieving a 44% genetic diagnosis rate.
METTL3, an m6A methyltransferase, is integral to the regulation of messenger RNA (mRNA) biogenesis, degradation, and translation through the N6-methyladenosine (m6A) modification. Alterations in m6A homeostasis have been implicated in the development, progression, invasion, and metastasis of certain cancers. The present research aims to examine the consequences of METTL3 knockdown using short hairpin RNA (shRNA) on the proliferation and invasive capabilities of human colorectal and melanoma cancer cell lines.
Introduction: Retinol has a long history of treating skin conditions, including photoaging. However, skin irritation with repeated use of retinol is well documented. The present study assessed the effectiveness of a novel topical formulation, referred to as retinol topical formulation (RTF), to improve the quality of skin health.
