AI Article Synopsis
- The study evaluated the sensitivity and specificity of a new immunochromatographic assay (ICA) kit, ALSONIC® Adeno, for detecting human adenovirus in throat swabs.
- The assay demonstrated a high sensitivity of 92.2% and specificity of 95.1%, showing promise as a reliable diagnostic tool.
- With a short incubation time of just 5 minutes, ALSONIC® Adeno could offer faster diagnosis compared to existing kits in Japan, making it advantageous for acute HAdV infections.
Article Abstract
Background: The aim of this study was to determine the sensitivity and specificity of a novel immunochromatographic assay (ICA) kit, ALSONIC® Adeno (Alfresa Pharma Co., Osaka, Japan), for the detection of human adenovirus (HAdV) from throat swab samples based on the results of real-time PCR. The incubation time required for the novel assay kit (5 minutes) is shorter than that required for other ICA kits that are available in Japan.
Methods: Throat swab samples were taken from 151 patients aged 6 months to 15 years who were suspected of having respiratory tract infections caused by HAdV.
Results: The sensitivity and specificity of the ICA for detection of HAdV were 92.2% (83/90) and 95.1% (58/61), respectively, and the assay showed positive and negative predictive values of 96.5% (83/86) and 89.2% (58/65), respectively.
Conclusions: ALSONIC® Adeno is suitable as a diagnostic tool in the acute phase of HAdV infection.
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| http://dx.doi.org/10.7754/Clin.Lab.2018.180420 | DOI Listing |
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