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Parkinsonism Relat Disord
August 2023
Center for Neurological Restoration, Department of Neurology, Neurological Institute, Cleveland Clinic, OH, United States. Electronic address:
Int J Emerg Med
May 2022
Department of Emergency Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.
Background: A well-known anesthetic, lidocaine is the most widely used local anesthetic. Local anesthetic systemic toxicity (LAST) is a life-threatening event with common and prominent presentations of central nervous system (CNS) toxicity and cardiovascular toxicity. The most frequent and prominent early warning signs and symptoms of LAST are central nervous system symptoms.
View Article and Find Full Text PDFMed Phys
May 2021
Department of Medical Physics, Wuhan University, Wuhan, 430072, China.
Purpose: Accurate dose calculation is a critical step in proton therapy. A novel machine learning-based approach was proposed to achieve comparable accuracy to that of Monte Carlo simulation while reducing the computational time.
Methods: Computed tomography-based patient phantoms were used and three treatment sites were selected (thorax, head, and abdomen), comprising different beam pathways and beam energies.
Cureus
November 2020
Cardiology, New York Presbyterian Queens, New York, USA.
ST-segment elevation (STE) in the lead aVR indicates global ischemia of the myocardium and is often associated with obstructive coronary artery disease (CAD). We report a serial of cases presenting with STE in aVR and diffuse ST depressions in more than six other leads as a common feature, but of different etiologies, i.e.
View Article and Find Full Text PDFMol Genet Metab
August 2019
Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, NC, USA.
Introduction:: Morbidity and mortality in adults with late-onset Pompe disease (LOPD) results primarily from persistent progressive respiratory muscle weakness despite treatment with enzyme replacement therapy (ERT). To address this need, we have developed a 12-week respiratory muscle training (RMT) program that provides calibrated, individualized, and progressive pressure-threshold resistance against inspiration and expiration. Our previous results suggest that our RMT regimen is safe, well-tolerated, and results in large increases in respiratory muscle strength.
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