Purpose: To compare wound healing performed with cold blade (CSB) and ultrasonic harmonic scalpel (UHS) in the abdominal aponeurosis of rats.
Methods: Eighty Wistar rats divided into two groups and underwent midline incision in the linea alba with cold blade and harmonic ultrasonic scalpel. Analysis were performed in subgroups of 10 animals after 3, 7, 14 and 21 days. Macroscopically was observed the presence of hematoma, infection, wound dehiscence, fistula and adherences. Microscopically were used collagen and immunohistochemical staining methods.
Results: Macroscopic, complications showed no statistical difference. Immunohistochemical analysis for MMP-9 was more intense in UHS group (p<0.05). TGF β presented its lower expression in UHS group at 14 and 21 days, with no statistical difference at 3 and 7 days (p<0.05). α-AML expression appeared higher in UHS group after 14 days and remained similar in others (p<0.05). Collagen deposition had no change in type I, and increased in type III in UHS; at 7th day the deposition was higher in CSB group; at 14th was similar in both groups (p<0.001).
Conclusion: UHS compared to the CSB has higher lesion area at the time of the incision; as well as it led to the delay of regeneration and scar maturation process.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1590/s0102-865020180090000004 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A Comparison Between Combined Ultrasonic and Bipolar Shears to Other Energy-Based Devices in Otolaryngology: A Systematic Review and Meta-Analysis.
Surg Innov
January 2025
Department of Otolaryngology - Head & Neck Surgery, Kirk Kerkorian School of Medicine at UNLV, Las Vegas, NV, USA.
Objective: The Thunderbeat (TB) is a new surgical device that combines ultrasonic and bipolar energy. The objective of this study is to examine how the combined ultrasonic and bipolar shears affect surgical outcomes when compared to other methods.
Data Sources And Review Methods: Using the PRISMA guidelines, the researchers used broad search terms in PubMed, Embase, and Web of Science, which produced a total of 2823 initial results, with years ranging from 1955 to June 2024.
Sutureless FOCUS harmonic scalpel versus clamp-and-tie techniques for thyroidectomy: A meta-analysis of 43 randomized controlled trials.
Int J Surg
October 2024
Department of Surgery, Sapienza University of Rome, Rome, Italy.
Background: One of the most important surgical steps during thyroidectomy is the safe ligation of vessels. In fact, it is crucial to avoid postoperative bleeding and nerves' injury. The "clamp and tie" technique was first introduced in the 19th century.
View Article and Find Full Text PDFUltrasonic Differentiation Between Two Species of Chinese Pygmy Dormice (Genus Typhlomys) With Support for the Size-Signal Allometry Hypothesis.
Integr Zool
December 2024
College of Biological and Pharmaceutical, China Three Gorges University, Yichang, Hubei Province, China.
The genus Typhlomys comprises six species that all exhibit exceptional climbing agility in arboreal habitats, of which five have been established to use ultrasonic echolocation in the 80-120-kHz frequency range to navigate among tree branches. Here, we investigated the ultrasonic vocalizations of the remaining and recently recognized species, T. fengjiensis, and compared its ultrasonic and morphological traits with its sibling species T.
View Article and Find Full Text PDFInvestigation of a multi-frequency ultrasonic acoustic pressure source for acoustic agglomeration.
Ultrasonics
December 2024
Institute of Mechanical Science, Faculty of Mechanics, Vilnius Gediminas Technical University, Vilnius, Lithuania. Electronic address:
This paper represents numerical and experimental investigations of an ultrasonic multifrequency piezoelectric acoustic pressure source whose target application is acoustic agglomeration of fine and ultrafine particles. The operation of source is based on three vibration modes at 25.83 kHz, 34.
View Article and Find Full Text PDFUtilizing the ultrasonic shear for internal mammary artery harvesting in minimally invasive coronary artery bypass grafting surgery is worth considering.
J Thorac Dis
November 2024
Department of Cardiac Surgery, Peking University Third Hospital, Beijing, China.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!