When used in tissue engineering, polymer nanofibers with magnetic and electrical functionality could promote the growth of tissues and cells by applying magnetic and electric stimulation. Short nanofibers with these properties, which have a high specific surface area and can be arranged through magnetic induction, have potential applications in the fields of materials and biomedical engineering. In this study, poly(lactic-co-glycolic acid) (PLGA) nanofibers with nano-Fe₃O₄ particles were subjected to electrostatic spinning to obtain superparamagnetic Fe₃O₄/PLGA nanofibers. After being processed in a homogenizer, graphene/Fe₃O₄/PLGA short nanofibers with a length of 11.90±2.03 m and a diameter of 256.5±13.7 nm were prepared by deposition. The effects of the PLGA concentration and graphene concentration on the morphology, size and conductivity of short fibers were studied by scanning electron microscopy (SEM) and conductivity testing. The chemical composition of the short fibers was characterized by Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). The magnetic properties of the short fibers were characterized by using a vibrating sample magnetometer (VSM). Superparamagnetic and conductive PLGA nanofibers with a conductivity of 9.34×10 S/m were obtained for further applications.
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http://dx.doi.org/10.1166/jnn.2019.16400 | DOI Listing |
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