Introduction: Operative correction of symptomatic bunionette by means of minimally invasive (MI) osteotomies of the 5th metatarsal (M5) has gained popularity. This study aims to investigate the safe zones of commonly used techniques and the risk of injury to neurological structures.
Materials And Methods: Ten human fresh frozen cadaveric feet were dissected and branches of the sural nerve were identified. A frontal section of the feet was performed at the site of the skin incision described for M5 MI osteotomies (corresponding to distal and mid diaphyseal osteotomies). The location of the lateral dorsal cutaneous nerve (LDCN) of the sural nerve or its branches was documented using a goniometer and o'clock references placed on the frontal section of the M5.
Results: The LDCN showed variations in the distribution of its branches, forming the dorsolateral branch - a single terminal branch for the 5th toe - in 6/10 cases or two terminal branches - the dorsolateral and dorsomedial - in 4/10. At the point of osteotomies, the dorsolateral branch was identified at a mean of 22.7° from the extensor tendon around the M5 circumference and in all cases between 12 and 2 o'clock in a right foot or 10 o'clock to 12 o'clock in a left.
Conclusion: The studied M5 osteotomies can place the dorsolateral branch of the fifth toe at risk and safe zones lie between 10 o'clock to 2 o'clock in any foot laterality. If these landmarks are considered, the risk of nerve damage is minimized when performing MI osteotomies of the M5.
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http://dx.doi.org/10.1016/j.foot.2018.02.004 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Center for Brain Circuit Therapeutics, Department of Neurology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115.
Deep brain stimulation is an efficacious treatment for dystonia. While the internal pallidum serves as the primary target, recently, stimulation of the subthalamic nucleus (STN) has been investigated. However, optimal targeting within this structure and its surroundings have not been studied in depth.
View Article and Find Full Text PDFSci Rep
January 2025
Women's Operational Military Exposure Network Center of Excellence (WOMEN COE), VA Palo Alto Health Care System, Palo Alto, USA.
Anhedonia, a core symptom of depression, has been defined as the loss of pleasure or lack of reactivity to pleasurable stimuli. Considering the relevance of alpha asymmetry to MDD and anhedonia, we explored the effect of dorsolateral prefrontal cortex (DLPFC) stimulation on frontal and posterior EEG alpha asymmetry (FAA and PAA, respectively), in this exploratory investigation. 61 participants randomly received sham (n = 11), bilateral (BS; n = 25), or unilateral stimulation (US; n = 25) of the DLPFC.
View Article and Find Full Text PDFBasic Clin Neurosci
July 2024
Department of Cognitive Modeling, Institute for Cognitive Science Studies, Tehran, Iran.
Introduction: Response inhibition is an impaired cognitive function in attention-deficit/hyperactivity disorder (ADHD) individuals. This primary deficit during the cancelation of an intended movement is observed even in the minimal demanding cognitive tasks. Studies have shown that transcranial magnetic stimulation (TMS), especially on the dorsolateral prefrontal cortex (DLPFC), can improve response inhibition.
View Article and Find Full Text PDFJ Affect Disord
February 2025
Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, Tainan, Taiwan; Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:
Background: The insula has a significant impact on interoception and depression. This study aims to explore the role of the insula in mediating treatment responses to high-frequency repetitive transcranial magnetic stimulation (rTMS) targeting the left dorsolateral prefrontal cortex (DLPFC).
Methods: Twenty-five patients with either bipolar disorder (BD, n = 15) or major depressive disorder (MDD, n = 10) were recruited.
CNS Neurosci Ther
November 2024
Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Aim: There is a lack of research on transcranial direct current stimulation (tDCS) for the treatment of somatic symptoms in major depressive disorder (MDD) and the suitable stimulating brain region. We investigated the efficacy of tDCS targeting the dorsolateral prefrontal cortex (DLPFC) versus orbitofrontal cortex (OFC) on depressive somatic symptoms and somatic anxiety in patients with MDD and aimed to identify the appropriate stimulating brain regions.
Methods: In this randomized, double-blind, sham-controlled study, a total of 70 patients diagnosed with MDD were randomly allocated into DLPFC group, OFC group, and Sham group.
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