Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181154 | PMC |
| http://dx.doi.org/10.5688/ajpe7294 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The efficacy and safety of tyrosine kinase inhibitors in the treatment of advanced or metastatic chordoma: a single-arm meta-analysis.
Neurosurg Rev
January 2025
Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45# Changchun Street, Xicheng District, Beijing, China.
Chordoma is a rare malignant tumor with a higher incidence in males than in females. There is an increasing number of clinical studies related to tyrosine kinase inhibitors (TKIs), yet the efficacy and safety of different drugs vary. In this single-arm meta-analysis evaluating the efficacy and safety of TKIs for chordoma treatment, 12 studies involving 365 patients were analyzed.
View Article and Find Full Text PDFPatient and public involvement in academic clinical research in Switzerland - a mixed methods study.
Swiss Med Wkly
December 2024
Clinical Trials Center Zurich, University Hospital Zurich, Zurich, Switzerland.
Background: While patient and public involvement (PPI) in clinical research contributes substantially to research ethics, feasibility and quality, the uptake and implementation of PPI-based approaches in Switzerland remain unknown. This study aimed to evaluate the current state and acceptance of PPI in academic clinical research in Switzerland, with the goal of developing recommendations for its future implementation and development.
Methods: A sequential explanatory mixed-methods study was conducted to assess the current landscape and acceptance of PPI in academic clinical research across different stakeholder groups in Switzerland.
A Strategic Approach to Shift Diversity, Equity, and Inclusion Culture in Physical Therapy Education.
J Phys Ther Educ
January 2025
Beth P. Davis is the associate professor in the Department of Rehabilitation Medicine at the Emory University School of Medicine, 1441 Clifton Road NE, Suite 312, Atlanta, GA 30322 Please address all correspondence to Beth P. Davis.
Background And Purpose: Efforts focused on racial and ethnic diversity in Doctor of Physical Therapy (DPT) programs have been prioritized to increase enrollment of Underrepresented in Medicine (URiM) individuals. While increasing diversity is a positive step, this Program took strategic action to embed Diversity, Equity, and Inclusion (DEI)-informed principles into all program areas. This holistic approach catalyzed a cultural shift that reflects a deepened commitment to the society we serve.
View Article and Find Full Text PDFNewly identified SpoVAF/FigP complex: the role in spore germination at moderate high pressure and influencing factors.
Appl Environ Microbiol
January 2025
College of Food Science and Nutritional Engineering, National Engineering Research Center for Fruit and Vegetable Processing, Key Laboratory of Fruit and Vegetable Processing of Ministry of Agriculture and Rural Affairs, Beijing Key Laboratory for Food Non-Thermal Processing, China Agricultural University, Beijing, China.
Unlabelled: The SpoVAF/FigP complex, a newly identified dormant spore ion channel, has been shown to amplify the response of germinant receptors (GRs) to nutrient germinants. However, its contribution to high-pressure-induced germination remains unexplored. In this study, we discovered that the 5AF/FigP complex played an important role in the GR-dependent germination of spores under moderate high pressure (MHP) by facilitating the release of ions, such as potassium (K), a mechanism in parallel with its role in nutrient-induced germination.
View Article and Find Full Text PDFHypoxia Promotes Malignant Progression of Colorectal Cancer by Inducing POSTN Cancer-Associated Fibroblast Formation.
Mol Carcinog
January 2025
School of Medicine, Southeast University, Nanjing, China.
Colorectal cancer (CRC) is one of the most common malignancies. Hypoxia can promote the occurrence and development of CRC. However, how hypoxia regulates the CRC immune microenvironment needs to be further explored.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!