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Void spot assay (VSA) noninvasively evaluates urination. VSA is often not performed in rats due to difficulty analyzing larger papers compared with mouse. This study optimizes VSA for rats by comparing post-assay visualization techniques: bright field light (BF), ultraviolet light (UV), and ninhydrin spray (N).
View Article and Find Full Text PDFHiking Trails Facilitate the Spread of a Native High-Arctic Species.
Ecol Evol
January 2025
Dynamic Macroecology/Land Change Science Swiss Federal Institute for Forest, Snow and Landscape Research WSL Birmensdorf Switzerland.
High-Arctic environments are facing an elevated pace of warming and increasing human activities, making them more susceptible to the introduction and spread of alien species. We investigated the role of human disturbance in facilitating the spread of a native plant () in a high-Arctic natural environment close to Isfjord Radio station and along adjacent hiking trails at Kapp Linné, Svalbard. We reconstructed the spatial pattern of the arrival and spread of at Kapp Linné by combining historical records of the species occurrence (1928-2018) with a contemporary survey of the plant abundance along the main hiking trail (2023 survey) and tested the relative effects of altitude and proximity to hiking trails on the species density via a generalised linear model (GLM).
View Article and Find Full Text PDFBeyond despair: Leveraging ecosystem restoration for psychosocial resilience.
Proc Natl Acad Sci U S A
January 2025
Division of Marine Science and Conservation, Nicholas School of the Environment, Duke University Marine Lab, Beaufort, NC 28516.
Ecosystem restoration has historically been viewed as an ecological endeavor, but restoration possesses significant, yet largely untapped, potential as a catalyst for personal and social transformation. We highlight the opportunity for restoration to enhance community resilience by increasing agency and collective action and countering the pervasive perception that we are powerless witnesses to environmental decline. In this perspective, we take a "bright spots" approach and highlight successful examples of ecosystem restoration that have helped to nurture a sense of place, foster optimism, and cultivate stronger and more diverse social networks.
View Article and Find Full Text PDFFemtomolar hydrogen sulfide detection via hybrid small-molecule nano-arrays.
Nat Commun
December 2024
College of Engineering and Applied Sciences, Jiangsu Key Laboratory of Artificial Functional Materials, Nanjing University, Nanjing, China.
Early disease diagnosis hinges on the sensitive detection of signaling molecules. Among these, hydrogen sulfide (HS) has emerged as a critical player in cardiovascular and nervous system signaling. On-chip immunoassays, particularly nanoarray-based interfacial detection, offer promising avenues for ultra-sensitive analysis due to their confined reaction volumes and precise signal localization.
View Article and Find Full Text PDFEffects of Retinol, Natural Pea Peptide and Antioxidant Blend in a Topical Formulation: In Vitro and Clinical Evidence.
Dermatol Ther (Heidelb)
December 2024
Department of Cell Biology and Physiology, The Neuroscience Center, College of Life Sciences, Brigham Young University, Provo, UT, 84602, USA.
Introduction: Retinol has a long history of treating skin conditions, including photoaging. However, skin irritation with repeated use of retinol is well documented. The present study assessed the effectiveness of a novel topical formulation, referred to as retinol topical formulation (RTF), to improve the quality of skin health.
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