During the whole life of oil production, enhancing the efficiency and optimizing the production of wells always have been discussed. Formation damage is one of the most frequent reasons for oil wells productivity reduction. This phenomenon can be caused by different factors such as fine migration, drilling mud invasion, asphaltene precipitation, capillary blockage reservoir fluids, and inorganic precipitation. Acidizing and hydraulic fracturing are two conventional well treatment methods usually applied to overcome the formation damage. However, due to destructive side effects of these methods, new methods such as Ultrasonic technology have helped to overwhelm these challenges. The usefulness of this method has been previously proven experimentally and operationally, but the effect of this technology on the pore structure has not been completely explored yet. In this paper, the effect of the ultrasonic wave on the pore structure during well stimulation is investigated. For this purpose, five samples of carbonate and sandstone with different rock textures were investigated to determine the effect of ultrasonic waves on flow behavior and microscopic pore structure through absolute permeability test, scanning electron microscope (SEM) images and petrography. The results showed that ultrasonic waves may affect pore structure through; initiation of micro-fracture and/or detachment of rock particle. The micro-fracture initiation is expected to increase the permeability while the detached particle may reduce or increase permeability through the clogging or opening the pore throat. For example, it was observed that ultrasonic waves significantly increase the permeability of Oolitic carbonate samples, while the controversial changes were observed in sandstone samples.
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http://dx.doi.org/10.1016/j.ultsonch.2018.10.002 | DOI Listing |
Chin J Nat Med
December 2024
Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Chinese Medicine, Nanchang 330004, China; State Key Laboratory for the Modernization of Classical and Famous Prescriptions of Chinese Medicine, Nanchang 330096, China; Research and Development Department, Jiangzhong Pharmaceutical Co., Ltd., Nanchang 330004, China. Electronic address:
Essential oils (EOs) are natural, volatile substances derived from aromatic plants. They exhibit multiple pharmacological effects, including antibacterial, anticancer, anti-inflammatory, and antioxidant properties, with broad application prospects in health care, food, and agriculture. However, the instability of volatile components, which are susceptible to deterioration under light, heat, and oxygen exposure, as well as limited water solubility, have significantly impeded the development and application of EOs.
View Article and Find Full Text PDFJ Pharm Sci
December 2024
Division of Pharmaceutical Sciences, College of Pharmacy, University of Cincinnati, Cincinnati, OH 45267. Electronic address:
Previous studies of RNA nanoparticles have demonstrated the potential of these nanoparticles in ocular delivery via the subconjunctival route. Sustained ocular delivery is beneficial for chronic eye disease treatment, and utilizing a reservoir implant in the periocular space (e.g.
View Article and Find Full Text PDFAquat Toxicol
December 2024
Drug Theoretics and Cheminformatics Laboratory, Department of Pharmaceutical Technology, Jadavpur University, 188 Raja S C Mullick Road, 700032, Kolkata, India. Electronic address:
Early life stage (ELS) toxicity testing in fish is a crucial test procedure used to evaluate the long-term effects of a wide range of chemicals, including pesticides, industrial chemicals, pharmaceuticals, and food additives. This test is particularly important for screening and prioritizing thousands of chemicals under the Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) regulation. In silico methods can be used to estimate the toxicity of a chemical when no experimental data is available and to reduce the cost, time, and resources involved in the experimentation process.
View Article and Find Full Text PDFPLoS One
December 2024
Civil Engineering Department, Lanzhou Jiaotong University, Lanzhou, China.
The Belt and Road strategy has significantly advanced the scale of infrastructure construction in the Qinghai-Tibet Plateau permafrost area. Consequently, this demands higher requirements on the strength and frost resistance of concrete (FRC) cured under low-temperature and negative-temperature conditions. Accordingly, in this study, tests on the mechanical properties and FRC were conducted under standard curing, 5 °C curing, and -3 °C curing conditions.
View Article and Find Full Text PDFBioprocess Biosyst Eng
December 2024
Department of Biological Engineering, Inha University, 100 Inha-Ro, Nam-Gu, Incheon, 22212, Republic of Korea.
Experimental models for exploring abnormal brain blood vessels, including ischemic stroke, are crucial in neuroscience; recently, significant attention has been paid to artificial tissues through tissue engineering. Nanofibers, although commonly used as tissue engineering scaffolds, undergo structural deformations easily, making it challenging to create uniform tissue, especially for the smallest-diameter ones such as perforating arteries. This study focused on the development of a platform capable of reconstructing structurally and functionally replicated perforating arteries.
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