AI Article Synopsis
- Migraine and ADHD have been found to co-occur in adults, similar to previous findings in children and adolescents, indicating a potential linked pathology.
- The study gathered data from over 26,000 Danish blood donors, using validated questionnaires and logistic regression to establish a connection between the two disorders.
- Results show a strong association between migraine and ADHD, particularly in females and with migraines that have visual disturbances, suggesting further research into genetic and environmental factors is needed.
Article Abstract
Background: Migraine and Attention Deficit and Hyperactivity Disorder (ADHD) have been found to be associated in child and adolescent cohorts; however, the association has not been assessed in adults or otherwise healthy population. Assessing the comorbidity between ADHD and migraine may clarify the etiopathology of both diseases. Thus, the objective is to assess whether migraine (with and without visual disturbances) and ADHD are comorbid disorders.
Methods: Participants from the Danish Blood Donor Study (N = 26,456, age 18-65, 46% female) were assessed for migraine and ADHD using the ASRS ver 1.1 clinically validated questionnaire and self-reported migraine in a cross-sectional study. Logistic regression was used to examine the comorbidity between migraine and ADHD, and their associated endophenotypes.
Results: Migraine was strongly associated with ADHD (OR = 1.8, 95% CI = 1.5-2.1), (238/6152 vs 690/19,376). There was a significant interaction between age and gender, with comorbidity increasing with age and female sex. Post-hoc analysis showed that migraine with visual disturbance was generally associated with a marginally higher risk of ADHD and this was independent of ADHD endophenotypes.
Conclusion: Migraine and ADHD were demonstrated to be comorbid disorders; the association with ADHD was most prominent for participants with migraine with visual disturbances. Future studies will elucidate which genetic and environmental factors contribute to migraine-ADHD comorbidity.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190553 | PMC |
| http://dx.doi.org/10.1186/s12883-018-1149-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A decade of pyridine-containing heterocycles in US FDA approved drugs: a medicinal chemistry-based analysis.
RSC Med Chem
October 2024
Department of Pharmaceutical Sciences, Chauras Campus, HNB Garhwal University (A Central University) Srinagar Uttarakhand 246174 India
Heterocyclic scaffolds, particularly, pyridine-containing azaheterocycles, constitute a major part of the drugs approved in the past decade. In the present review, we explored the pyridine ring part of US FDA-approved small molecules (2014-2023). The analysis of the approved drugs bearing a pyridine ring revealed that a total of 54 drugs were approved.
View Article and Find Full Text PDFReasons for Use and Perceived Effects of Medical Cannabis: A Cross-Sectional Statewide Survey.
Med Cannabis Cannabinoids
July 2024
Department of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, FL, USA.
Introduction: Medical cannabis (MC) is available upon certification for one of several qualifying conditions in Florida, USA. Previous studies suggested that some people seek cannabis for medical conditions/symptoms beyond those legally permitted. However, data remain limited on patient motives for seeking MC and their experiences around its impact on their health.
View Article and Find Full Text PDFInternalizing disorders rather than ADHD are risk factors for chronicity in pediatric migraine patients.
Turk J Med Sci
October 2024
Department of Neurology, Faculty of Medicine, Mersin University, Mersin, Turkiye.
Background/aim: Migraine is a prevalent neurological disorder that can lead to disability in children and adolescents. It is frequently accompanied by psychiatric comorbidities, both internalizing and externalizing disorders. While the relationship between migraine and internalizing disorders has been studied, there is limited research on the link between migraine and attention deficit hyperactivity disorder (ADHD).
View Article and Find Full Text PDFIdentifying the 'Miserable Minority' Among Pediatric Patients Following Concussion.
J Pediatr Surg
October 2024
Department of Orthopedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA; UPMC Sports Concussion Program, USA.
Objectives: To investigate whether there are empirically-detectable subgroups of concussion severity and recovery across three consecutive concussions, as well as to define risk factor and clinical assessment differences across subgroups.
Methods: The present study was a retrospective chart review of 202 adolescents 13.17 ± 1.
Brief Report: Under-Identification of Symptomatic Menopause in Publicly-Insured Autistic People.
J Autism Dev Disord
August 2024
A.J. Drexel Autism Institute, Drexel University, Philadelphia, PA, USA.
Article Synopsis
- * The research focused on autistic females aged 35-70 to examine the prevalence of symptomatic menopause and associated health conditions among them, finding about 4% reported symptomatic menopause.
- * Results showed that those with ADHD, anxiety, depression, migraines, and other conditions had higher rates of symptomatic menopause, highlighting the need for better support and discussions around these issues in healthcare settings.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!