Neutron radiation can deteriorate mechanical properties of the concrete materials, and thus it is questionable that neutron transport properties of concrete can remain unchanged during the life span of biological shielding walls. one-speed neutron diffusion equation and heat conduction equation were used as governing equations for prediction of neutron radiation and thermal field in concrete, respectively. The potential variations of transport properties due to neutron radiation and elevated temperature were estimated. A simplified example of a typical concrete biological shielding wall was analyzed up to 80 years, and the results were discussed. The radiation damage and radiation heating lead to minor changes of the temperature profile in the concrete. However, neutron radiation and elevated temperature can result in considerable increases of neutron flux and fluence in the concrete. The damage of concrete induced by neutron radiation and elevated temperature can considerably accelerate the penetration of neutron radiation into the concrete. This work is the first attempt to deal with the degradation of neutron and heat transport properties of concrete and its effect on neutron fluence distribution in concrete, and provides a possible way to determine the long-term neutron and thermal fields in concrete biological shielding walls.
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http://dx.doi.org/10.1016/j.jhazmat.2018.09.080 | DOI Listing |
Appl Radiat Isot
December 2024
Instituto de Física Corpuscular (CSIC-Universidad de Valencia), Valencia, Spain.
This paper explores the adaptation and application of i-TED Compton imagers for real-time dosimetry in Boron Neutron Capture Therapy (BNCT). The i-TED array, previously utilized in nuclear astrophysics experiments at CERN, is being optimized for detecting and imaging 478 keV gamma-rays, critical for accurate BNCT dosimetry. Detailed Monte Carlo simulations were used to optimize the i-TED detector configuration and enhance its performance in the challenging radiation environment typical of BNCT.
View Article and Find Full Text PDFAppl Radiat Isot
January 2025
Particle Radiation Oncology Research Center, Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2-Asashiro-Nishi, Kumatori-cho, Sennan-gun, Osaka, 590-0494, Japan.
Recent decades have seen the development of accelerator neutron sources suitable for installation in a hospital setting. Numerous challenges have been faced and solved to deliver technology which continues to transform the field of BNCT. This paper begins by briefly reviewing the technologies which are currently, or soon will be, in clinical use.
View Article and Find Full Text PDFTher Adv Med Oncol
January 2025
Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Via Alessandro Manzoni 56, 20089 Rozzano, Italy.
Objectives: A combination of chemotherapy and radiotherapy is employed in the curative and postoperative treatment of locally advanced head and neck cancers (HNC). Integrated chemoradiation (CRT) treatments result in a non-negligible rate of severe toxic effects. Treatment-related death (TRD) is a crucial topic for physicians involved in the curative treatment of HNC.
View Article and Find Full Text PDFDrug Dev Ind Pharm
January 2025
Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Objective: Boron Neutron Capture Therapy (BNCT) is a novel precision radiotherapy. The key to BNCT application lies in the effective targeting and retention of the boron-10 (B) carrier. Among the various compounds studied in clinical settings, 4-boronophenylalanine (BPA) become the most prevalent one currently.
View Article and Find Full Text PDFSensors (Basel)
December 2024
China Institute of Atomic Energy, P.O. Box 275 (26), Beijing 102413, China.
Fast-neutron reactors are an important representative of Generation IV nuclear reactors, and due to the unique structure and material properties of fast reactor fuel, traditional mechanical cutting methods are not applicable. In contrast, laser cutting has emerged as an ideal alternative. However, ensuring the stability of optical fibers and laser cutting heads under high radiation doses, as well as maintaining cutting quality after irradiation, remains a significant technical challenge.
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