A bio-derived sustainable medium based on water extract of pomegranate ash (WEPA) has, for the first time, been developed for the homocoupling of aryl halides under palladium-assistance. Avoiding the requirement of an external base, ligand and π-acid, the use of the proposed renewable medium offers remarkable attributes like wide substrate scope, good to nearly quantitative yields of biphenyls with exceptional chemoselectivity and scale up viability.
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