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This Journal of Biocommunication Gallery features a selection of the Best of Show Winners from 10 years of BioImages. We have selected the winning entries of the last decade to showcase the variety, breadth and depth of work in these award-winning images. BioImages is the BioCommunications Association's annual visual media competition that showcases the finest still, graphics and motion media work in the life sciences and medicine.
View Article and Find Full Text PDFWideband Tuning and Deep-Tissue Spectral Detection of Indium Phosphide Nano-Laser Particles.
bioRxiv
December 2024
Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Cambridge, Massachusetts, 02139, USA.
Laser particles (LPs) emitting narrowband spectra across wide spectral ranges are highly promising for high-multiplex optical barcoding. Here, we present LPs based on indium phosphide (InP) nanodisks, operating in the near-infrared wavelength range of 740-970 nm. Utilizing low-order whispering gallery resonance modes in size-tuned nanodisks, we achieved an ultrawide color palette with 27% bandwidth utilization and nanometer-scale linewidth.
View Article and Find Full Text PDFLive and let die: analyzing ultrastructural features in cell death.
Ultrastruct Pathol
January 2025
Department of Biology, Ecology and Earth Sciences, Centre for Microscopy and Microanalysis (CM2) Transmission Electron Microscopy Laboratory, University of Calabria, Cosenza, Italy.
Cell death is an important process that supports morphogenesis during development and tissue homeostasis during adult life by removing damaged or unwanted cells and its dysregulation is associated with numerous disease states. There are different pathways through which a cell can undergo cell death, each relying on peculiar molecular mechanisms and morpho-ultrastructural features. To date, however, while molecular and genetic approaches have been successfully integrated into the field, cell death studies rarely incorporate ultrastructural data from electron microscopy.
View Article and Find Full Text PDFWhispering Gallery Mode Micro/Nanolasers for Intracellular Probing at Single Cell Resolution.
ACS Sens
November 2024
Key Laboratory of Trans-scale Laser Manufacturing Technology, Ministry of Education, Beijing 100124, China.
Intracellular probing at single cell resolution is key to revealing the heterogeneity of cells, learning new cell subtypes and functions, understanding the pathophysiology of disease, and ensuring precise diagnosis and treatment. Despite the best efforts, an enormous challenge remains due to the very small size, extremely low content, and dynamic microenvironment of a single cell. Whispering gallery mode (WGM) micro/nanolasers (active WGM) offer unique advantages of small mode volume, high quality factors, bright and low threshold laser emission, and narrow line width, particularly suitable for integration within a single cell.
View Article and Find Full Text PDFRelativistic artificial molecule of two coupled graphene quantum dots at tunable distances.
Nat Commun
October 2024
Center for Advanced Quantum Studies, School of Physics and Astronomy, Beijing Normal University, Beijing, 100875, China.
Article Synopsis
- The study investigates the energy difference between bonding and antibonding orbitals in relativistic artificial molecules made from two graphene quantum dots with adjustable distances.
- Using a scanning tunneling microscope, the research visualizes how these artificial molecules form and shows that the energy difference between orbitals increases as the distance between the dots decreases.
- The findings reveal transitions in orbital shapes, from ring-like patterns to figure-eight structures, enhancing the understanding of quantum-relativistic matter at the nanoscale.
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