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http://dx.doi.org/10.1016/j.fertnstert.2018.06.038 | DOI Listing |
J Perioper Pract
January 2025
University of Derby, Derby, UK.
This historical research article offers a comprehensive examination of the evolution of cataract surgery from ancient practices to modern innovations. The historical trajectory of cataract treatment will be explored, beginning with ancient techniques such as couching in ancient civilisations and progressing through critical milestones in surgical advancement. The research delves into the challenges faced by early practitioners, the emergence of novel techniques and the pivotal contributions of pioneering surgeons throughout history.
View Article and Find Full Text PDFBiol Imaging
December 2024
Visual Information Laboratory, University of Bristol, Bristol, UK.
Optical coherence tomography (OCT) and confocal microscopy are pivotal in retinal imaging, offering distinct advantages and limitations. OCT offers rapid, noninvasive imaging but can suffer from clarity issues and motion artifacts, while confocal microscopy, providing high-resolution, cellular-detailed color images, is invasive and raises ethical concerns. To bridge the benefits of both modalities, we propose a novel framework based on unsupervised 3D CycleGAN for translating unpaired OCT to confocal microscopy images.
View Article and Find Full Text PDFJ Recept Signal Transduct Res
December 2024
Department of Dravyaguna, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
CDK12 is essential for cellular processes like RNA processing, transcription, and cell cycle regulation, inhibiting cancer cell growth and facilitating macrophage invasion. CDK12 is a significant oncogenic factor in various cancers, including HER2-positive breast cancer, Anaplastic thyroid carcinoma, Hepatocellular carcinoma, prostate cancer, and Ewing sarcoma. It is also regarded as a potential biomarker, emphasizing its broader significance in oncology.
View Article and Find Full Text PDFJ Physiol
January 2025
Marine Mammal Research Program, Hawai'i Institute of Marine Biology, University of Hawai'i at Mānoa, Kāne'ohe, HI, USA.
Improving our understanding of energy allocation in reproduction is key for accurately parameterizing bioenergetic models to assess population responses to environmental perturbations and anthropogenic disturbance. We quantified the energetic cost of gestation in humpback whales (Megaptera novaeangliae) using historical whaling records, non-invasive unoccupied aerial system (UAS) photogrammetry and post mortem tissue samples. First, we estimated relative birth size using body length measurements of 678 mother-fetus pairs from historical whaling records and 987 mother-calf pairs measured in situ using UAS-photogrammetry.
View Article and Find Full Text PDFExpert Rev Mol Med
December 2024
Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA.
Tuberculosis (TB) is one of the deadliest infectious diseases globally, ranking as 13th leading cause of mortality and morbidity. According to the Global Tuberculosis Report 2022, TB claimed the lives of 1.6 million people worldwide in 2021.
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