Patients who suffer from ulcers often experience pain of sufficient severity to reduce their quality of life. The aim of this review article is to collect, analyze and qualitatively resynthesize information regarding the definition and prevalence of ulcer pain, the pathophysiology of such pain, its assessment, and the optimal systemic and topical treatments. Early identification and prompt treatment are key to pain management. Further management should focus on appropriate dressing as much as on pain medication. The goal is to provide maximum relief with minimum side-effects.
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http://dx.doi.org/10.1016/j.maturitas.2018.08.013 | DOI Listing |
Orv Hetil
January 2025
2 Semmelweis Egyetem, Általános Orvostudományi Kar, Aneszteziológiai és Perioperatív Betegellátó Intézet Budapest, Üllői út 78/B, 1082 Magyarország.
Am J Cardiovasc Drugs
January 2025
Pediatric Nephrology, State University of Campinas, São Paulo, Brazil.
Around one-quarter of all patients undergoing cardiac procedures, particularly those on cardiopulmonary bypass, develop cardiac surgery-associated acute kidney injury (CSA-AKI). This complication increases the risk of several serious morbidities and of mortality, representing a significant burden for both patients and the healthcare system. Patients with diminished kidney function before surgery, such as those with chronic kidney disease, are at heightened risk of developing CSA-AKI and have poorer outcomes than patients without preexisting kidney injury who develop CSA-AKI.
View Article and Find Full Text PDFCell Mol Biol (Noisy-le-grand)
January 2025
Department of Pharmacology, Faculty of Pharmacy, Mersin University, Mersin, Türkiye.
Pak J Pharm Sci
January 2025
Department of Pathobiology and Biomedical Sciences, Muhammad Nawaz Sharif University of Agriculture, Multan, Pakistan/Ali-Ul-Murtaza Department of Rehabilitation Sciences, Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan.
This study aimed to evaluate the efficacy of vinegar-soaked Ficus carica fruits (VSFCF) for managing cholelithiasis in adults. A parallel-group, single-blinded, randomized controlled trial at Noreen Nishat Welfare Hospital, Khanewal, Pakistan, was conducted from December 2023 to February 2024. Fifty adults with ultrasound-confirmed cholelithiasis were randomly assigned to receive either VSFCF (1 g/kg/day) or ursodiol (600 mg/day).
View Article and Find Full Text PDFPilot Feasibility Stud
January 2025
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
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