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Efficacy of a novel patient-focused intervention aimed at increasing adherence to guideline-based preventive measures in asplenic patients: the PrePSS trial.
Infection
December 2023
Division of Infectious Diseases, Department of Medicine II, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Article Synopsis
- The study aimed to evaluate if a new telephone intervention improves adherence to preventive measures for asplenic patients at risk of post-splenectomy sepsis (PSS), comparing it to usual care.
- The researchers enrolled 106 patients in a novel health action process approach (HAPA)-based intervention and compared their outcomes to a historical control group of 113 patients using a specific scoring system called the PrePSS score.
- Results showed a significant increase in adherence scores for the intervention group (mean score 7.70) versus the control group (mean score 3.73), indicating that this intervention could be beneficial for better management of at-risk asplenic patients.
Management of patients explanted for implantable cardioverter defibrillator infections: Bridge therapy with external temporary ICD.
Pacing Clin Electrophysiol
November 2021
Division of Cardiology, University of Eastern Piedmont, Maggiore della Carità Hospital, Novara, Italy.
Aims And Methods: In case of cardiacimplantable electronicdevice (CIED)-related infections, it is mandatory to completely remove the device and administer prolonged antibiotic therapy. The management of patients explanted for an implantable defibrillator (ICD) infection is complex especially in patients needing anti-bradycardia pacing or tachyarrhythmia protection. We tested the efficacy and safety of a conventional ICD externally connected to a transvenous dual-coil lead as bridging therapy before the reimplant, comparing outcomes with a historical cohort of patients (N = 113) treated with temporary transvenous pacing.
View Article and Find Full Text PDFSymptoms of infectious diseases in HIV-positive travellers: A prospective study with exposure-matched controls.
Travel Med Infect Dis
July 2019
Department of Infectious Diseases, Public Health Service (GGD) of Amsterdam, Amsterdam, the Netherlands; National Coordination Centre for Travellers' Health Advice (LCR), Amsterdam, the Netherlands; Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Center, Amsterdam Infection & Immunity Institute (AIII), University of Amsterdam, the Netherlands.
Background: Recently, the number of HIV-infected travellers to (sub)tropical areas has increased substantially. In the Netherlands, HIV-positive travellers with CD4-cells of <500/mm are advised to carry stand-by antibiotic treatment against travellers' diarrhoea. Our aim was to determine whether HIV infection is associated with travel-related symptomatic diseases.
View Article and Find Full Text PDFStand-by antibiotics for travellers' diarrhoea: risks, benefits and research needs.
J Travel Med
January 2018
Enteric Diseases Department, Naval Medical Research Center, Silver Spring, MD, USA.
Stand-by antibiotics encourage unwarranted use of antibiotics for travelers' diarrhea: A prospective study.
Travel Med Infect Dis
April 2019
Inflammation Center, Division of Infectious Diseases, University of Helsinki and Helsinki University Hospital, P.O. Box 348, FI-00029, Finland; Unit of Infectious Diseases, Department of Medicine/Solna, Karolinska Institutet, SE-17176 Stockholm, Sweden; Travel Clinic, Aava Medical Center, Annankatu 32, FI-00100 Helsinki, Finland. Electronic address:
Background: As antibiotics predispose travelers to acquiring multidrug-resistant intestinal bacteria, they should no longer be considered a mainstay for treating travelers' diarrhea. It has been claimed that stand-by antibiotics are justified as a means to avoid visits to local healthcare providers which often lead to polypharmacy.
Method: We revisited the traveler data of 316 prospectively recruited volunteers with travelers' diarrhea by retrieving from questionnaires and health diaries information on antibiotic use, stand-by antibiotic carriage, and visits with local healthcare.
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