STEREOCONTROLLED SYNTHESIS OF HIV-l PROTEASE INHIBITORS WITH C-AXIS OF SYMMETRY.

Tetrahedron Lett

Department of Medicinal Chemistry, Merck Sharp & Dohme Research Laboratories, West Point, Pennsylvania 19486.

Published: October 1991

An efficient and stereocontrolled synthesis of various C-symmetric HIV-l protease inhibitors is described, starting from commercially available and inexpensive D-mannitol.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177228PMC
http://dx.doi.org/10.1016/S0040-4039(00)93541-XDOI Listing

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