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Triple Threat: How Global Fungal Rice and Wheat Pathogens Utilize Comparable Pathogenicity Mechanisms to Drive Host Colonization.
Mol Plant Microbe Interact
January 2025
University of Florida, Microbiology and Cell Science, Gainesville, Florida, United States;
Plant pathogens pose significant threats to global cereal crop production, particularly for essential crops like rice and wheat, which are fundamental to global food security and provide nearly 40% of the global caloric intake. As the global population continues to rise, increasing agricultural production to meet food demands becomes even more critical. However, the production of these vital crops is constantly threatened by phytopathological diseases, especially those caused by fungal pathogens such as , the causative agent of rice blast disease, , responsible for head blight (FHB) in wheat, and , the source of Septoria tritici blotch (STB).
View Article and Find Full Text PDFUnion Rates Following Power Rasp Joint Preparation for Foot and Ankle Arthrodesis: A Retrospective Study of 418 Fusions.
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Surgical Fellow, Florida Orthopedic Foot & Ankle Center Fellowship, 5741 Bee Ridge Rd #490, Sarasota, FL 34233. Electronic address:
Joint arthrodesis is a very common surgical approach in foot and ankle surgery at various anatomic levels. Several techniques have demonstrated the ability to provide successful fusion with appropriate preparation of the joint in question. With that in mind, the joint preparation, regardless of approach or instrumentation, is consistently the most time-consuming.
View Article and Find Full Text PDFDysregulated Signaling Pathways in Canine Mammary Tumor and Human Triple Negative Breast Cancer: Advances and Potential Therapeutic Targets.
Int J Mol Sci
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Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China.
In 2022, human breast cancer (HBC) and canine mammary tumors (CMTs) remained the most prevalent malignant tumors worldwide, with high recurrence and lethality rates, posing a significant threat to human and dog health. The development of breast cancer involves multiple signaling pathways, highlighting the need for effective inhibitory drugs that target key proteins in these pathways. This article reviews the dysregulation of the EGFR, PI3K/AKT/mTOR, Hippo, pyroptosis, and PD-1/PD-L1 signaling pathways in HBC and CMT, as well as the corresponding drugs used to inhibit tumor growth, with the aim of providing theoretical support for the development of more efficient drugs.
View Article and Find Full Text PDFLiDAR-Based Negative Obstacle Detection for Unmanned Ground Vehicles in Orchards.
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Institute of Agricultural Equipment, Zhejiang Academy of Agricultural Sciences, Hangzhou 310012, China.
In orchard environments, negative obstacles such as ditches and potholes pose significant safety risks to robots working within them. This paper proposes a negative obstacle detection method based on LiDAR tilt mounting. With the LiDAR tilted at 40°, the blind spot is reduced from 3 m to 0.
View Article and Find Full Text PDFFirst detection of the S989P+V1016G+D1763Y haplotype and expansion of voltage-gated sodium channel mutations in Aedes aegypti in Taiwan in 2016-2023.
PLoS Negl Trop Dis
January 2025
Center for Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan.
Background: Aedes aegypti transmits various arthropod-borne diseases such as dengue, posing a significant burden to public health in tropical and subtropical regions. Pyrethroid-based control strategies are effective in managing this vector; however, the development of insecticide resistance has hindered these efforts. Hence, long-term monitoring of insecticide resistance in mosquito populations is crucial for effective vector and disease control.
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