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Venom immunization: IgG/IgE titers, safety, risk, and methods of the VIPRBITEM cohort.
J Biol Methods
October 2024
University of Texas Rio Grande Valley School of Medicine, 1201 West University Drive, Edinburg, TX 78539, USA.
Background: This is the first study to examine a cohort that engages in the practice of immunization with snake venoms. In this practice, either fresh wet venom or venom reconstituted from freeze-dried form is used in vaccination protocols to produce hyper-immunity to venom.
Methods: This is a retrospective community-initiated collaborative research (CICR) project that collated the records of venom immunization.
Food availability has direct and delayed effects on structural growth and body reserves in garter snakes.
Ecology
January 2025
Department of Ecosystem Science and Management, Pennsylvania State University, University Park, Pennsylvania, USA.
Phenotypic plasticity in body growth enables organisms to cope with unpredictable paucities in resource availability. Growth traits influence survival and reproductive success, and thereby, population persistence, and early-life resource availability may govern lifetime patterns in growth, reproductive success, and survival. The influence of early-life environment is decidedly consequential for indeterminately growing ectotherms, which rely on available resources and ambient temperatures to maximize fitness throughout life.
View Article and Find Full Text PDFChronic implantable flexible serpentine probe reveals impaired spatial coding of place cells in epilepsy.
Natl Sci Rev
February 2025
State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100190, China.
The development of minimally invasive and reliable electrode probes for neural signal recording is crucial for advancing neuroscience and treating major brain disorders. Flexible neural probes offer superior long-term recording capabilities over traditional rigid probes. This study introduces a parylene-based serpentine electrode probe for stable, long-term neural monitoring.
View Article and Find Full Text PDFSpatial Accessibility Analysis of Snake Antivenom.
Int J Public Health
January 2025
School of Public Health, Hainan Medical University, Haikou, Hainan Province, China.
Objectives: To analyze the spatial accessibility of antivenom immunizing agents equipped hospitals in Hainan Province.
Methods: This paper analyzes the spatial accessibility of medical institutions equipped with different types of snake antivenom using network analysis and two-step mobile search method, and evaluates the service level and spatial accessibility of medical institutions equipped with different types of antivenom immunizing agents in Hainan Province from the perspectives of both supply and demand.
Results: The number of people in Hainan Province who need to spend more than 1 h to reach an antivenom, antivenom, antivenom, antivenom equipped hospital, and equipped with antivenom for all species of snakes in the country is approximately 856,000, 231,300, 3,071,000, 2,666,000 and 4,721,000 people, respectively.
New Frontiers in Fighting Mycobacterial Infections: Venom-Derived Peptides.
Probiotics Antimicrob Proteins
January 2025
Department of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.
Notwithstanding the indefatigable endeavors to develop effective anti-mycobacterial therapies, mycobacterial infections still present a tough problem for medicine today. The problem is further complicated by the disquieting surge of drug-resistant mycobacterial pathogens, which considerably narrows the existing therapeutic options. Thus, there is a genuine need to discover novel anti-mycobacterial drugs.
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