Chronic Exposure to Solvents Among Construction Painters: Reductions in Exposure and Neurobehavioral Health Effects.

J Occup Environ Med

Rutgers University, Environmental & Occupational Health Sciences Institute, Piscataway, New Jersey (Drs Fiedler, Weisel, Kipen, Laumbach), Rutgers University School of Public Health, Piscataway, New Jersey (Drs Fiedler, Weisel, Kipen, Laumbach, Ohman-Strickland), Merck & Company Inc., Kenilworth, New Jersey (Dr Nwankwo), Mount Sinai School of Medicine, Pain and Fatigue Study Center, New York, New York (Dr Lange).

Published: December 2018

AI Article Synopsis

  • The study aimed to evaluate the neurobehavioral impact of lifetime exposure to solvents by comparing painters with similar demographic controls.
  • Results indicated that while there were some subtle performance differences in tests of verbal learning and motor skills among exposed painters, overall cognitive function did not show significant decline.
  • The findings suggest that despite some individual test variations, the decline in solvent concentrations in paints over time may have reduced the potential adverse effects on cognitive performance.

Article Abstract

Objective: The aim of this study was to assess the neurobehavioral effects of lifetime solvent exposure by comparing the performance of painters and demographically comparable controls.

Methods: Performance of exposed painters (N = 133) was compared with unexposed tapers, glaziers, or carpenters (N = 78) on the following domains: motor/perceptual speed, visual contrast, attention, working memory/planning, and visual and verbal memory. Lifetime exposure was estimated with questionnaires, field measurements, and paint composition.

Results: After controlling for confounders, lifetime solvent exposure did not predict reduction in performance for overall domains of function. Lifetime solvent exposures predicted subtle alterations for individual tests of verbal learning, motor coordination, and visuospatial accuracy.

Conclusion: Concentrations of solvents in paints have steadily declined during the working lifetime of subjects in this study. Although reduced performance was observed on individual tests, these alterations were not consistent across tests and unlikely to be of clinical significance.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289817PMC
http://dx.doi.org/10.1097/JOM.0000000000001470DOI Listing

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