AI Article Synopsis
- Group V Phospholipase A (Pla2g5) is part of a family of enzymes that generate lipids and is found in various immune and non-immune cells.
- The enzyme's expression increases in response to certain diseases and plays different roles depending on the context.
- The review discusses both the protective and harmful effects of Pla2g5, based on studies conducted in labs and in clinical settings.
Article Abstract
Group V Phospholipase A (Pla2g5) is a member of the PLA family of lipid-generating enzymes. It is expressed in immune and non-immune cell types and is inducible during several pathologic conditions serving context-specific functions. In this review, we recapitulate the protective and detrimental functions of Pla2g5 investigated through preclinical and translational approaches. This article is part of a Special Issue entitled Novel functions of phospholipase A Guest Editors: Makoto Murakami and Gerard Lambeau.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432776 | PMC |
| http://dx.doi.org/10.1016/j.bbalip.2018.10.001 | DOI Listing |
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