Pericytes: The Brain's Very First Responders?

Neuron

Gladstone Institutes, San Francisco, CA 94158, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

Published: October 2018

Infection can negatively impact brain functions. Here, Duan et al. (2018) show that specific PDGFRβ-expressing cell subtypes of the neurovascular unit release the chemokine CCL2 rapidly after systemic infection, leading to increased neural excitability.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701953PMC
http://dx.doi.org/10.1016/j.neuron.2018.09.033DOI Listing

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