Hyponatremia after anticoagulant treatment: a rare cause of adrenal failure.

Endocrinol Diabetes Metab Case Rep

Endocrinology, Niguarda Hospital, Milan, Italy

Published: September 2018

A 69-year-old male was admitted for severe hyponatremia disclosed after an accidental fall. He was anticoagulated from 2 months after the implantation of a biologic aortic valve prosthesis. The work-up disclosed adrenal failure and MRI showed bilateral adrenal hemorrhage. Clinical picture and lab parameters normalized quickly after the appropriate replacement treatment. Anticoagulation excess should be added to the list of drugs potentially causing hyponatremia. Learning points: •• Hyponatremia requires a complete and timely workup in order to start an appropriate treatment for the improvement of clinical conditions. •• History is crucial: a detailed list of drugs potentially causing hyponatremia should be collected. Anticoagulants should be added to the list, mostly in the event of excessive anticoagulation. •• Intra-adrenal hemorrhage is a rare cause of hyponatremia and adrenal failure. •• The ACTH test is still the gold standard for the diagnosis of hypoadrenalism.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169550PMC
http://dx.doi.org/10.1530/EDM-18-0101DOI Listing

Publication Analysis

Top Keywords

adrenal failure
12
list drugs
8
drugs causing
8
causing hyponatremia
8
hyponatremia
6
hyponatremia anticoagulant
4
anticoagulant treatment
4
treatment rare
4
adrenal
4
rare adrenal
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!