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Quercetagetin and patuletin were extracted by the same method from two different species that have multiple uses in folk medicine in Mexico and around the globe, one of which is as an anticancer agent. Their biological activity (IC and necrotic, apoptotic and selective activities of these flavonols) was evaluated and compared to that of quercetin, examining specifically the effects of C6 substitution among quercetin, quercetagetin and patuletin. We find that the presence of a methoxyl group in C6 enhances their potency.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222523 | PMC |
| http://dx.doi.org/10.3390/molecules23102579 | DOI Listing |
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