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Efficacy and safety of intravenous ferric carboxymaltose in the treatment of Restless Legs Syndrome: a systematic review and meta-analysis.
Front Neurol
January 2025
Department of Public Health, Atish Dipankar University of Science and Technology, Dhaka, Bangladesh.
Introduction: Restless Legs Syndrome (RLS), also known as Willis-Ekbom Disease (WED), is a sensorimotor disorder characterized by an uncontrollable urge to move the legs, typically accompanied by discomfort. Low iron levels, pregnancy, and age are some identified risk factors. RLS is treated using various pharmacological options, including dopamine agonists, benzodiazepines, anticonvulsants, opioids, and bupropion.
View Article and Find Full Text PDFRisk Factors and Pain Management in the Incidence of Postoperative Delirium in Elderly Patients: A Retrospective Study.
J Clin Med
December 2024
AP-HM, Department of Anesthesiology and Critical Care Medicine, University Hospital Timone, Aix Marseille University, 13005 Marseille, France.
: Postoperative delirium (POD) is a common surgical complication that increases hospital stay duration, hospitalization costs, readmission rates and mortality. This study aims to describe the incidence of POD in an elderly patient population and to investigate pain assessment as a risk factor for postoperative confusion. Additionally, we aim to determine a predictive model for POD.
View Article and Find Full Text PDFIn long-term users of benzodiazepine receptor agonists, direct-to-patient interventions vs. usual care reduced use at 6 mo.
Ann Intern Med
January 2025
Medical University of South Carolina, Charleston, South Carolina, USA (S.P.H.).
GIM/FP/GP: [Formula: see text] Geriatrics: [Formula: see text].
View Article and Find Full Text PDFImproving the physical health of overweight/obese people suffering from severe mental disorders: What is the role of antipsychotic drugs and of lifestyle psychosocial interventions?
J Psychiatr Res
January 2025
Department of Psychiatry, University of Campania "Vanvitelli", Italy.
People with severe mental disorders experience premature mortality compared with the general population. Several factors contribute to the mortality gap, including the adoption of unhealthy lifestyle behaviours, poor screening for physical illnesses, difficulties in accessing healthcare facilities, specific clinical features of mental disorders and some pharmacological treatment such as antipsychotic medications with serious metabolic side effects. In the present study, carried out in the framework of the LIFESTYLE trial, a funded nationwide multicentric study, we aimed to assess the impact of different antipsychotics in mediating the effectiveness of psychosocial intervention on healthy lifestyle behaviours.
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