We report a case of congenital adrenal hyperplasia in a 29 year old patient, who presented with testicular pain, bilateral testicular masses, and oligospermia. Ultrasonography confirmed, in both testis, the presence of heterogeneous and hypoechoic lesions with irregular borders and internal and peripheral vascularization. Seric tumor markers were negative. The patient was scheduled for perioperative testicular biopsy and bilateral orchiectomy. Perioperative biopsy was suggestive of testicular adrenal rest tumor and not additional procedure was performed. Treatment was initiated with high doses of glucocorticoids, decreasing the size of testicular masses and testicular pain was alleviated.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.androl.2017.10.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Long-term Complications and Testicular Adrenal Rest Tumors in Congenital Adrenal Hyperplasia.
J Clin Res Pediatr Endocrinol
December 2024
Ankara University, Pediatric Endocrinology, Ankara, Turkey.
Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency accounts for approximately 95% of all CAH cases and is one of the most common inborn errors of metabolism. While glucocorticoid therapy has significantly improved patient outcomes, the focus has shifted towards managing the long-term effects. Numerous adverse outcomes have been associated with CAH, including those resulting from supraphysiological doses of glucocorticoid and mineralocorticoid replacement, excessive adrenal androgen secretion, and elevated levels of steroid precursors and adrenocorticotropic hormone (ACTH).
View Article and Find Full Text PDFEditorial: 46,XX differences of sex development (DSD) outside congenital adrenal hyperplasia (CAH).
Front Endocrinol (Lausanne)
November 2024
Section of Medicine, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.
Posterior retroperitoneal adrenalectomy for metastatic disease: a multi-site Australian series.
ANZ J Surg
November 2024
Surgical Services, John Hunter Hospital, New Lambton Heights, New South Wales, Australia.
Background: Posterior retroperitoneoscopic adrenalectomy (PRA) for isolated adrenal metastasis is minimally invasive, may prolong survival and improve quality of life. The current evidence base is scant.
Methods: A multi-site retrospective analysis of all cases of PRA for adrenal metastasis between 2011 and 2023, by four high-volume adrenal surgeons was performed.
Gonadal changes in children and adolescents with congenital adrenal hyperplasia.
J Pediatr Endocrinol Metab
December 2024
Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Article Synopsis
- Testicular adrenal rest tumors (TARTs) are found in 50% of male patients with congenital adrenal hyperplasia (CAH), which can lead to infertility.
- The study involved 50 patients (30 females and 20 males) undergoing imaging tests to assess gonadal health and analyze genetic data.
- Findings suggest that while TARTs are prevalent in males, routine ovarian imaging in females with CAH is unnecessary unless they show signs of ovarian dysfunction.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!