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An experimental test of eco-evolutionary dynamics on rocky shores.
Ecology
January 2025
Bodega Marine Laboratory, University of California Davis, Bodega Bay, California, USA.
A growing body of theoretical studies and laboratory experiments has focused attention on reciprocal feedbacks between ecological and evolutionary processes. However, uncertainty remains about whether such eco-evolutionary feedbacks have an important or negligible influence on natural communities. Thus, recent discussions call for field experiments that explore whether selection on phenotypic variation within populations leads to contemporaneous effects on community dynamics.
View Article and Find Full Text PDFDissimilatory nitrate reduction pathways drive high nitrous oxide emissions and nitrogen retention under the flash drought in the largest freshwater lake in China.
Water Res
December 2024
Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 211135, China; Sino-Danish Centre for Education and Research, University of Chinese Academy of Sciences, Beijing 100039, China; Poyang Lake Wetland Research Station, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Jiujiang 332899, China. Electronic address:
Flash drought (FD) events induced by climate change may disrupt the normal hydrological regimes of floodplain lakes and affect the plant-microbe mediated dissimilatory nitrate reduction (DNR), i.e., denitrification, anammox and dissimilatory nitrate reduction to ammonium (DNRA), thus having important consequences for nitrous oxide (NO) emissions and nitrogen (N) retention.
View Article and Find Full Text PDFSNORA37/CMTR1/ELAVL1 feedback loop drives gastric cancer progression via facilitating CD44 alternative splicing.
J Exp Clin Cancer Res
January 2025
Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, Hubei Province, People's Republic of China.
Background: Emerging evidence shows that small nucleolar RNA (snoRNA), a type of highly conserved non-coding RNA, is involved in tumorigenesis and aggressiveness. However, the roles of snoRNAs in regulating alternative splicing crucial for cancer progression remain elusive.
Methods: High-throughput RNA sequencing and comprehensive analysis were performed to identify crucial snoRNAs and downstream alternative splicing events.
m6A-modified circSTX6 as a key regulator of cervical cancer malignancy via SPI1 and IL6/JAK2/STAT3 pathways.
Oncogene
January 2025
Department of Gynecological Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
In recent years, circRNAs have garnered increasing attention for their role in cervical cancer. However, the functions of many newly identified circRNAs remain unclear and require further exploration. In this study, we investigated the expression and oncogenic potential of the novel circRNA circSTX6 in cervical cancer.
View Article and Find Full Text PDFThe TRP Channels Serving as Chemical-to-Electrical Signal Converter.
Physiol Rev
January 2025
Department of Physiology and Membrane Biology, University of California, Davis, School of Medicine, Davis CA, 95616, USA.
Biology uses many signaling mechanisms. Among them, calcium and membrane potential are two prominent mediators for cellular signaling. TRPM4 and TRPM5, two calcium-activated monovalent cation-conducting ion channels, offer a direct linkage between these two signals.
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