AI Article Synopsis
- A surface-enhanced Raman scattering (SERS) platform was developed for detecting trace amounts of mercury (Hg) ions, utilizing gold nanoparticles (AuNPs) modified with a poly-thymine aptamer and 2-naphthalenethiol (2-NT) as a Raman reporter.
- The platform showed a limit of detection (LOD) of 1.0 parts per trillion (ppt), significantly lower than the World Health Organization’s drinking water limit of 10.0 parts per billion (ppb).
- The sensor is cost-effective, requires simple sample preparation, and minimizes false positives, demonstrating its effectiveness in analyzing trace mercury in lake water samples.
Article Abstract
A surface-enhanced Raman scattering (SERS) platform for the selective trace analysis of Hg ions was reported, based on poly-thymine (T) aptamer/2-naphthalenethiol (2-NT)-modified gold nanoparticles (AuNPs), which was an oligonucleotide-functionalized nanosensor and SERS chip. 2-NT was used as a Raman reporter, and T aptamer could form a T-Hg-T structure with Hg ions making an SERS nanosensor absorbed to the SERS chip. The optimum concentrations of DNA and 2-NT were obtained. An average of 960 DNA molecules attached to each AuNP were measured. The limit of detection (LOD) was 1.0 ppt (1.0 × 10 g/mL), which is far below the limit of 10.0 ppb for drinking water, stipulated by the World Health Organization. The sensor has the advantages of low detection cost, a simple sample pretreatment, a green solution and reducing false positives. Furthermore, the nanosensor was used for the determination of trace Hg in the water of a lake; a reliable result was obtained accurately.
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| http://dx.doi.org/10.2116/analsci.18P381 | DOI Listing |
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