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Bacterial Pathogen Profiles and Antibiotic Resistance in Pediatric Leukemia Patients: Insights for Optimizing Infection Management in Immunocompromised Children.
Antibiotics (Basel)
December 2024
Department of Mother and Baby, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
This study investigates bacterial etiology and antibiotic resistance in pediatric leukemia patients to determine the impact of chronic pathology on treatment efficacy. : Thirty cases of children aged 1-16 years (18 boys, 12 girls) were analyzed, identifying 13 pathogens, including 8 Gram-positive and 5 Gram-negative bacteria. : Among the patients, 11 girls presented with acute lymphoblastic leukemia (ALL) type B, while one boy and one girl had acute myeloid leukemia, and, as for boys, three had ALL type T and two had pre-B ALL.
View Article and Find Full Text PDFSevere Panton-Valentine-Leukocidin-Positive Infections in Pediatric Age: A Case Report and a Literature Review.
Antibiotics (Basel)
December 2024
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro", University of Palermo, 90127 Palermo, Italy.
Infections caused by S. aureus strains encoding Panton-Valentine leukocidin (PVL-SA) have become increasingly relevant in community settings and can cause severe conditions in pediatric populations. We present the pediatric case of an invasive disease caused by PVL-SA and provide a literature review of severe manifestations caused by these strains in children.
View Article and Find Full Text PDF[Examination of Capsule Genotypes, Antibiotic Susceptibility Profiles and Biofilm Forming Abilities of Group B Streptococcus Isolates Isolated from Pregnant Women].
Mikrobiyol Bul
October 2024
Çukurova University Faculty of Medicine, Department of Medical Microbiology, Adana, Türkiye.
Group B Streptococcus (GBS) or Streptococcus agalactiae is a pathogen that causes infections during pregnancy. The aim of this study was to investigate the antibiotic sensitivity profiles, capsule genotypes and biofilm forming capabilities of GBS isolates obtained from pregnant women . The study included 252 pregnant women who applied to Adana Gynecology and Children's Hospital between 2018 and 2023.
View Article and Find Full Text PDFAntibiotic susceptibility testing and molecular characterization based on whole-genome sequencing of isolates from pediatric infections at the National Regional Medical Center of Southwest China during the COVID-19 pandemic.
Front Public Health
December 2024
Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, China.
Background: is a transmitted respiratory pathogen that causes high morbidity and mortality in children, especially those under 5 years of age. During the implementation of population control measures for COVID-19 in mainland China, the detection rate in pediatric patients decreased. However, with the second wave of the COVID-19 pandemic (2022), the incidence of pneumococcal disease (PD) and even invasive pneumococcal disease (IPD) began to rise again.
View Article and Find Full Text PDFInvestigation of integron classes 1, 2, and 3 among multi-drug resistant Staphylococcus aureus isolates in Iran: a multi-center study.
BMC Infect Dis
December 2024
Zoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, Iran.
Background: Rising methicillin-resistant Staphylococcus aureus (MRSA) poses a global health threat, contributing to serious infections with high mortality rates. Integrons are recognized as significant genetic elements in disseminating multidrug-resistant (MDR) strains. This study focuses on assessing the prevalence of integron classes 1, 2, and 3 in S.
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