We propose a flexible form-fittingMRI receiver coil array assembledby individualcoilmodules. This design targetsMRI applications requiring a receiver array conforming to the anatomy of various shapes or sizes. Coil modules in our proposed array were arranged with gaps between them. Each coil module had a circumferential shielding structure stacked on top of the coil. Together they achieve robust decoupling when the array was bent differently. Two types of the circumferential shielding structure were investigatedby using full-wave electromagnetic simulations and imaging experiments. Results showed that our flexible coil array had good decoupling between coils whether they were on a flat or curved surface with the S21 magnitude ranged between -18.1 dB and -19.9 dB in simulations, and with the average of off-diagonal entries of the noise correlationmatrix less than 0.047 in experimentalmeasurements. Anatomical images of human brain, calf, and knee were acquired by our seven-channel prototype on a 3T MRI system. The maximal and the average SNR within 50 mm from our array surpassed those from the commercial 32-channel head and 4-channel flexible coil arrays by 2.63/1.35-fold and 3.89/1.50-fold, respectively.
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http://dx.doi.org/10.1109/TMI.2018.2873317 | DOI Listing |
Magn Reson Med Sci
January 2025
Department of Biomedical Engineering, Gachon University, Seongnam, Gyeonggi, Korea.
Purpose: Hyperthermia is a treatment that applies heat to damage or kill cancer cells and can be also used for drug deliveries. It is important to apply the heat into the specific area in order to target the cancer tissue and avoid damaging healthy tissue. For this reason, the development of heat applicators that have the capability to deliver the heat to the target area is vital.
View Article and Find Full Text PDFFront Oncol
January 2025
Department of Radiology, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Background: In the realm of breast cancer diagnosis and treatment, accurately discerning molecular subtypes is of paramount importance, especially when aiming to avoid invasive tests. The updated guidelines for diagnosing and treating HER2 positive advanced breast cancer, as presented at the 2021 National Breast Cancer Conference and the Annual Meeting of the Chinese Society of Clinical Oncology, highlight the significance of this approach. A new generation of drug-antibody combinations has emerged, expanding the array of treatment options for HER2 positive advanced breast cancer and significantly improving patient survival rates.
View Article and Find Full Text PDFIEEE J Solid-State Circuits
November 2024
Department of Electrical and Computer Engineering, Rice University, Houston TX, 77005, USA.
Miniature bioelectronic implants promise revolutionary therapies for cardiovascular and neurological disorders. Wireless power transfer (WPT) is a significant method for miniaturization, eliminating the need for bulky batteries in today's devices. Despite successful demonstrations of millimetric battery-free implants in animal models, the robustness and efficiency of WPT are known to degrade significantly under misalignment incurred by body movements, respiration, heart beating, and limited control of implant orientation during surgery.
View Article and Find Full Text PDFMed Phys
January 2025
Department of Electrical and Electronics Engineering, Bilkent University, Ankara, Turkey.
Background: Radiofrequency (RF) transmit arrays play a crucial role in various MRI applications, offering enhanced field control and improved imaging capabilities. Designing and optimizing these arrays, particularly in high-field MRI settings, poses challenges related to coupling, resonance, and construction imperfections. Numerical electromagnetic simulation methods effectively aid in the initial design, but discrepancies between simulated and fabricated arrays often necessitate fine-tuning.
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