Objective: Candidal species identification in malignant and potentially malignant oral lesions with antifungal susceptibility.
Materials And Methods: Oral candidal carriage, strain diversity, and antifungal susceptibility of were checked for the patients having oral cancer or precancer reporting to the clinics for 1½ year. Statistically significant patients were selected and a control group was taken. A total of 105 individuals were selected and divided into three different groups. Salivary samples were taken from all the individuals. detection was done using Sabouraud's agar and candidal species detection on CHROMagar. antifungal sensitivity was done using antifungal disc diffusion method.
Results: was isolated from 88.6% of patients with oral cancer and 45.7% in oral precancerous group. was the predominant species found in 100% of oral precancerous and 71% in oral cancerous patients. Other a species found were (9.7%) and (19.6%). Antifungal susceptibility showed 4.3% sensitivity to fluconazole and 100% sensitivity to amphotericin B and nystatin.
Conclusion: Oral carriage was higher in oral cancerous group and majority of them were sensitive to amphotericin B and nystatin.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169267 | PMC |
| http://dx.doi.org/10.4103/ccd.ccd_296_18 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Extracellular phospholipase, protease and hemolysin production by strains of opportunistic yeasts from the excreta of Mew Gulls breeding in natural and urban habitats.
Vet Res Commun
January 2025
Soil Science Faculty, Lomonosov Moscow State University, Moscow, 119234, Russia.
Extracellular hydrolytic activity (phospholipase, protease and hemolysin production) was evaluated in 178 strains of potentially pathogenic ascomycetous (Candida parapsilosis, Candida tropicalis) and basidiomycetous (Rhodotorula mucilaginosa) yeasts isolated from the excreta of Mew Gulls. Two bird colonies, one nesting in a natural habitat and the other in an urban habitat at the landfill, were studied simultaneously during their 7-month breeding season. Significant differences in phospholipase and protease production were found between natural and anthropophized strains.
View Article and Find Full Text PDFA Narrative Review of Invasive Candidiasis in the Intensive Care Unit.
Ther Adv Pulm Crit Care Med
December 2024
Department of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organization, (MICRO), St James' Hospital, Dublin, Ireland.
species is the most common cause of invasive fungal infection in the critically ill population admitted to the intensive care unit (ICU). Numerous risk factors for developing invasive candidiasis (IC) have been identified, and some, like the breach of protective barriers, abound within the ICU. Given that IC carries a significant mortality, morbidity, and healthcare cost burden, early diagnosis and treatment have become an essential topic of discussion.
View Article and Find Full Text PDFThe (1,3)-β-D-glucan use for invasive candidiasis diagnosis in non-neutropenic critically ill patients: a prospective cohort study.
Tunis Med
December 2024
University of Tunis El Manar, Faculty of Medicine of Tunis, La Rabta Tertiary Hospital, Intensive Care Medicine Department, 1007, Tunis, Tunisia.
Unlabelled: Introduction Invasive candidiasis (IC) is a widespread infection in intensive care. As culture-based diagnostic techniques take several days before positivity and leaks of sensitivity. (1,3)-β-D-glucan (BDG) was proposed as a mycological criterion for IC diagnosis in selected patients.
View Article and Find Full Text PDFThe appropriate nutrient conditions for methicillin-resistant Staphylococcus aureus and Candida albicans dual-species biofilm formation in vitro.
Sci Rep
January 2025
Department of Biological and Medical Sciences, Charles University, Faculty of Pharmacy in Hradec Králové, 2089, Zborovská, Hradec Králové, 500 03, Czech Republic.
Polymicrobial biofilms, the reason for most chronic wound infections, play a significant role in increasing antibiotic resistance. The in vivo effectiveness of the new anti-biofilm therapy is conditioned by the profound evaluation using appropriate in vitro biofilm models. Since nutrient availability is crucial for in vitro biofilm formation, this study is focused on the impact of four selected cultivation media on the properties of methicillin-resistant Staphylococcus aureus and Candida albicans dual-species biofilms.
View Article and Find Full Text PDFThe frequency and clinical features of posttransplant pneumonia in solid-organ transplantation recipients: A transplant center experience.
Tuberk Toraks
December 2024
Department of Medical Microbiology, Dokuz Eylül University Faculty of Medicine, İzmir, Türkiye.
Introduction: In solid-organ transplant (SOT) recipients, while survival rates have improved with immunosuppressive therapies, the risk of opportunistic infections has also increased. This study aimed to evaluate the frequency of pneumonia, identify microbiological factors, investigate diagnostic methods, and analyse prognosis.
Materials And Methods: A retrospective study was conducted to identify adult SOT recipients referred to the pulmonary diseases department with a preliminary pneumonia diagnosis between 2011 and 2019.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!