Recent advances in the applications of metabolomics in eye research.

Anal Chim Acta

Singapore Eye Research Institute, Singapore; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Ophthalmology and Visual Science Academic Clinical Research Program, Duke-NUS Graduate Medical School, Singapore. Electronic address:

Published: December 2018

Metabolomics, the identification and quantitation of metabolites in a system, have been applied to identify new biomarkers or elucidate disease mechanism. In this review, we discussed the application of metabolomics in several ocular diseases and recent developments in metabolomics regarding tear fluids analysis, data acquisition and processing.

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http://dx.doi.org/10.1016/j.aca.2018.01.060DOI Listing

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